Abstract
Stoichiometric reduction of artemisinin to dihydroartemisinin (DHA) has been successfully transferred from batch to continuous flow conditions with a significant increase in productivity and an increase in selectivity. The DHA space-time-yield of up to 1.6 kg h -1 L -1 was attained which represents a 42 times increase in throughput compared to that of conventional batch process.
Original language | English |
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Pages (from-to) | 1039-1042 |
Number of pages | 4 |
Journal | Organic Process Research and Development |
Volume | 16 |
Issue number | 5 |
DOIs | |
Publication status | Published - 18 May 2012 |
Externally published | Yes |
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry