Abstract
Dysbiosis is a prominent factor in numerous inflammatory conditions, with Ruminococcus gnavus, a prevalent gut microbe, implicated in inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), eczema, metabolic disorders, and rheumatic diseases. R. gnavus contributes to inflammation by producing an inflammatory polysaccharide and degrading mucin. The increasing evidence of elevated R. gnavus abundance in various inflammatory conditions suggests its potential as a therapeutic target. Despite this, there are limited studies on treatment strategies targeting R. gnavus. This article provides a comprehensive overview of the association between R. gnavus and diverse inflammatory conditions, highlighting the need for further research to explore effective treatment options against this bacterium.
Original language | English |
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Article number | a0000396 |
Journal | Progress in Microbes and Molecular Biology |
Volume | 6 |
Issue number | 1 |
DOIs | |
Publication status | Published - 4 Jan 2023 |
Externally published | Yes |
Keywords
- Ruminococcus gnavus
- SDG 3 Good health and well-being
- gut microbiome
- inflammatory diseases
- probiotics
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology (miscellaneous)
- Microbiology (medical)