TY - JOUR
T1 - Spray dried nanoemulsions loaded with curcumin, resveratrol, and borage seed oil
T2 - The role of two different modified starches as encapsulating materials
AU - Rehman, Abdur
AU - Tong, Qunyi
AU - Jafari, Seid Mahdi
AU - Korma, Sameh A.
AU - Khan, Imran Mahmood
AU - Mohsin, Ali
AU - Manzoor, Muhammad Faisal
AU - Ashraf, Waqas
AU - Mushtaq, Bilal Sajid
AU - Zainab, Saadia
AU - Cacciotti, Ilaria
N1 - Publisher Copyright:
© 2021
PY - 2021/9/1
Y1 - 2021/9/1
N2 - Recently, food industries are directing on the promotion of innovative food matrices fortified with bioactive compounds in order to enhance the consumer's health. Octenyl succinic anhydride modified starches (OSA-MS) such as Hi-cap100 (HCP) and purity gum 2000 (PUG) were used to fabricate emulsions co-entrapped with borage seed oil (BSO), resveratrol (RES) and curcumin (CUR), which were further spray dried to obtain powders. The fabricated microcapsules loaded with BSO, RES, and CUR displayed excellent dissolution performance, high encapsulation efficiency (≈93.05%) as well as semi-spherical shape, revealed via scanning electron microscopy (SEM). We also evaluated the impact of storage time (4 weeks) and temperature (40 °C) on the physicochemical characterization of OSA-MS coated microcapsules. Microcapsules coated with HCP exhibited greater oxidative stability, lower water activity and moisture contents rather than PUG coated microcapsules during storage because of its good film-forming properties. Addition of CUR enhanced the oxidative stability and retention of bioactive compounds. HCP microcapsules loaded with BSO + RES + CUR presented supreme retention of RES (70.32%), CUR 81.6% and γ-linolenic acid (≈ 96%). Our findings showed that CUR acted as an antioxidant agent; also, lower molecular weight OSA-MS as wall material could be used for the entrapment of bioactive compounds and promotion of innovative food products.
AB - Recently, food industries are directing on the promotion of innovative food matrices fortified with bioactive compounds in order to enhance the consumer's health. Octenyl succinic anhydride modified starches (OSA-MS) such as Hi-cap100 (HCP) and purity gum 2000 (PUG) were used to fabricate emulsions co-entrapped with borage seed oil (BSO), resveratrol (RES) and curcumin (CUR), which were further spray dried to obtain powders. The fabricated microcapsules loaded with BSO, RES, and CUR displayed excellent dissolution performance, high encapsulation efficiency (≈93.05%) as well as semi-spherical shape, revealed via scanning electron microscopy (SEM). We also evaluated the impact of storage time (4 weeks) and temperature (40 °C) on the physicochemical characterization of OSA-MS coated microcapsules. Microcapsules coated with HCP exhibited greater oxidative stability, lower water activity and moisture contents rather than PUG coated microcapsules during storage because of its good film-forming properties. Addition of CUR enhanced the oxidative stability and retention of bioactive compounds. HCP microcapsules loaded with BSO + RES + CUR presented supreme retention of RES (70.32%), CUR 81.6% and γ-linolenic acid (≈ 96%). Our findings showed that CUR acted as an antioxidant agent; also, lower molecular weight OSA-MS as wall material could be used for the entrapment of bioactive compounds and promotion of innovative food products.
KW - Borage seed oil
KW - Curcumin
KW - Microcapsules
KW - Modified starches
KW - Physicochemical stability
KW - Resveratrol
UR - http://www.scopus.com/inward/record.url?scp=85110643836&partnerID=8YFLogxK
U2 - 10.1016/j.ijbiomac.2021.07.076
DO - 10.1016/j.ijbiomac.2021.07.076
M3 - Article
C2 - 34280445
AN - SCOPUS:85110643836
SN - 0141-8130
VL - 186
SP - 820
EP - 828
JO - International Journal of Biological Macromolecules
JF - International Journal of Biological Macromolecules
ER -
