Malaysia’s breakthrough in modern actinobacteria (Mod-actino) drug discovery research

Angel Yun Kuan Thye; Vengadesh Letchumanan; Loh Teng Hern Tan; Jodi Woan Fei Law; Learn Han Lee

doi:10.36877/pmmb.a0000275

Malaysia’s breakthrough in modern actinobacteria (Mod-actino) drug discovery research

Angel Yun Kuan Thye, Vengadesh Letchumanan, Loh Teng Hern Tan, Jodi Woan Fei Law, Learn Han Lee

Research output: Journal Publication › Review article › peer-review

16 Citations (Scopus)

Abstract

Actinobacteria are well-known producers of metabolites with medicinal value. The application of actinobacterial compounds has been expanded to other fields, including agriculture, aquaculture, and cosmeceutical. With this, the term “Modern Actinobacteria” (MOD-ACTINO) was first coined by a Malaysian researcher, Associate Professor Dr. Lee Learn Han, to define actinobacteria with modern applications. The present review aims to highlight the MOD-ACTINO research achievements in Malaysia. The Malaysian MOD-ACTINO strains are capable of exerting a wide range of bioactivities such as antimicrobial/anti-MRSA, anticancer, antioxidant, antifungal, and antimalarial. Research on MOD-ACTINO is highly encouraged to harness the benefits of actinobacteria and unravel important metabolites for various applications.

Original language	English
Article number	a0000275
Journal	Progress in Microbes and Molecular Biology
Volume	5
Issue number	1
DOIs	https://doi.org/10.36877/pmmb.a0000275
Publication status	Published - 20 Jan 2022
Externally published	Yes

Keywords

Actinomycetes
Anticancer
Antimicrobial
Antioxidant
Drug discovery
Modern actinobacteria
Streptomycetes

ASJC Scopus subject areas

Molecular Biology
Microbiology (medical)
Microbiology
Biochemistry, Genetics and Molecular Biology (miscellaneous)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.36877/pmmb.a0000275

Cite this

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title = "Malaysia{\textquoteright}s breakthrough in modern actinobacteria (Mod-actino) drug discovery research",

abstract = "Actinobacteria are well-known producers of metabolites with medicinal value. The application of actinobacterial compounds has been expanded to other fields, including agriculture, aquaculture, and cosmeceutical. With this, the term “Modern Actinobacteria” (MOD-ACTINO) was first coined by a Malaysian researcher, Associate Professor Dr. Lee Learn Han, to define actinobacteria with modern applications. The present review aims to highlight the MOD-ACTINO research achievements in Malaysia. The Malaysian MOD-ACTINO strains are capable of exerting a wide range of bioactivities such as antimicrobial/anti-MRSA, anticancer, antioxidant, antifungal, and antimalarial. Research on MOD-ACTINO is highly encouraged to harness the benefits of actinobacteria and unravel important metabolites for various applications.",

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author = "Thye, {Angel Yun Kuan} and Vengadesh Letchumanan and Tan, {Loh Teng Hern} and Law, {Jodi Woan Fei} and Lee, {Learn Han}",

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language = "English",

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AU - Thye, Angel Yun Kuan

AU - Letchumanan, Vengadesh

AU - Tan, Loh Teng Hern

AU - Law, Jodi Woan Fei

AU - Lee, Learn Han

PY - 2022/1/20

Y1 - 2022/1/20

N2 - Actinobacteria are well-known producers of metabolites with medicinal value. The application of actinobacterial compounds has been expanded to other fields, including agriculture, aquaculture, and cosmeceutical. With this, the term “Modern Actinobacteria” (MOD-ACTINO) was first coined by a Malaysian researcher, Associate Professor Dr. Lee Learn Han, to define actinobacteria with modern applications. The present review aims to highlight the MOD-ACTINO research achievements in Malaysia. The Malaysian MOD-ACTINO strains are capable of exerting a wide range of bioactivities such as antimicrobial/anti-MRSA, anticancer, antioxidant, antifungal, and antimalarial. Research on MOD-ACTINO is highly encouraged to harness the benefits of actinobacteria and unravel important metabolites for various applications.

AB - Actinobacteria are well-known producers of metabolites with medicinal value. The application of actinobacterial compounds has been expanded to other fields, including agriculture, aquaculture, and cosmeceutical. With this, the term “Modern Actinobacteria” (MOD-ACTINO) was first coined by a Malaysian researcher, Associate Professor Dr. Lee Learn Han, to define actinobacteria with modern applications. The present review aims to highlight the MOD-ACTINO research achievements in Malaysia. The Malaysian MOD-ACTINO strains are capable of exerting a wide range of bioactivities such as antimicrobial/anti-MRSA, anticancer, antioxidant, antifungal, and antimalarial. Research on MOD-ACTINO is highly encouraged to harness the benefits of actinobacteria and unravel important metabolites for various applications.

KW - Actinomycetes

KW - Anticancer

KW - Antimicrobial

KW - Antioxidant

KW - Drug discovery

KW - Modern actinobacteria

KW - Streptomycetes

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Malaysia’s breakthrough in modern actinobacteria (Mod-actino) drug discovery research

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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