Ocular anatomical and functional characteristics in anisometropic chinese children

Yuanyuan Zhong, Li Zeng, Zhi Chen, Jianlong Yang, Jiang Liu

Research output: Journal PublicationArticlepeer-review

3 Citations (Scopus)


SIGNIFICANCE: This research found that anterior and posterior biometrics differ in many aspects between fellow eyes of anisometropic children. This might shed light on the mechanisms underlying the onset and progression of anisometropia and myopia. PURPOSE: This study aimed to investigate the ocular biometric parameters, peripheral refraction, and accommodative lag of fellow eyes in anisometropic children. METHODS: Anisometropic children were recruited. Axial length (AL), vitreous chamber depth (VCD), central corneal thickness, anterior chamber depth (ACD), lens thickness (LT), simulated K readings, central and peripheral refractive errors, and accommodative lag were measured in both eyes. The subfoveal choroidal thickness, average choroidal thickness, and choroid vessel density of the 6 × 6-mmmacular area weremeasured by optical coherence tomography. RESULTS: Thirty-two children aged 11.1 ± 1.7 years were enrolled. The average degree of anisometropia was 2.49 ± 0.88 D. The AL, VCD, ACD, and simulated K reading values were significantly larger in the more myopic eyes, whereas the LT value was significantly smaller. Subfoveal choroidal thickness (P = .001) and average choroidal thickness (P = .02) were smaller in themoremyopic eyes than in the contralateral eyes, whereas choroid vessel density (P = .03) was larger. The amount of anisometropia had a significant positive correlation with the difference in AL (r = 0.869, P < .001), VCD (r = 0.853, P < .001), and ACD (r = 0.591, P < .001) and a negative correlation with the difference in LT (r = -0.457, P = .009). CONCLUSIONS: Ocular biometrics differ in many aspects between the fellow eyes of anisometropic Chinese children, and the difference is correlated with the degree of anisometropia.

Original languageEnglish
Pages (from-to)476-482
Number of pages7
JournalOptometry and Vision Science
Issue number5
Publication statusPublished - May 2021
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Optometry


Dive into the research topics of 'Ocular anatomical and functional characteristics in anisometropic chinese children'. Together they form a unique fingerprint.

Cite this