Electrogenerated chemiluminescence on smartphone with graphene quantum dots nanocomposites for Escherichia Coli detection

Shuang Li, Jinglong Liu, Zetao Chen, Yanli Lu, Sze Shin Low, Lihang Zhu, Chen Cheng, Yan He, Qingmei Chen, Bin Su, Qingjun Liu

Research output: Journal PublicationArticlepeer-review

44 Citations (Scopus)

Abstract

Graphene quantum dots (GQDs) have recently exhibited great potential in electrogenerated chemiluminescence (ECL) due to their catalyst and amplification effect towards luminophores. Here, we prepared GQDs nanocomposites to amplify the ECL signals in tris(2,2′-bipyridyl)ruthenium(II)/tripropylamine (Ru(bpy)32+/TPA) assay. Universal serial bus interface on smartphone was used as the excitation source for ECL. The luminescence signals were then captured by the smartphone camera and processed by a smartphone-based image analysis application (APP). By immobilizing layer of sensitive Escherichia coli (E.coli) antibody on the electrode surface, our smartphone-based ECL system exhibited excellent linear response towards detection of E.coli in the concentration range of 10 cfu/mL to 107 cfu/mL. Due to the vast popularity and portability of smartphone, the scope of application in our system would be able to greatly satisfy the need for point-of-care testing. Thus, in this work, the quantum dots-amplified luminescence detection was integrated with portable analytical devices, offering low-cost and real-time electrochemical analysis.

Original languageEnglish
Article number126811
JournalSensors and Actuators, B: Chemical
Volume297
DOIs
Publication statusPublished - 15 Oct 2019
Externally publishedYes

Keywords

  • Electrogenerated chemiluminescence (ECL)
  • Escherichia coli (E.coli)
  • Graphene quantum dots (GQDs)
  • Smartphone

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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