Deep Learning for Retina Structural Biomarker Classification Using OCT Images

Chi Xu, Huizhong Zheng, Keyi Liu, Yanming Chen, Chen Ye, Chenxi Niu, Shengji Jin, Yue Li, Haowei Gao, Jingxi Hu, Yuanhao Zou, Xiangjian He

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

This study presents an approach to identifying retinal structural biomarkers in ophthalmology, which is essential for accurate diagnosis and effective treatment of eye diseases. We develop a multi-modal, multi-task deep learning framework that integrates supervised and semi-supervised training methods. This model effectively processes a combination of 3D Optical Coherence Tomography (OCT) images and one-dimensional clinical data. A key advancement is introducing a custom post-processing method that significantly improves the precision of biomarker detection. Our model successfully identifies six distinct biomarkers in the retina and achieves a notable macro f1-score of 71.62%, representing a substantial 14.48% improvement over the baseline performance. This advancement underscores the potential of deep learning in enhancing diagnostic accuracy and treatment efficacy in ophthalmology.

Original languageEnglish
Title of host publicationInternational Workshop on Advanced Imaging Technology, IWAIT 2024
EditorsMasayuki Nakajima, Phooi Yee Lau, Jae-Gon Kim, Hiroyuki Kubo, Chuan-Yu Chang, Qian Kemao
PublisherSPIE
ISBN (Electronic)9781510679924
DOIs
Publication statusPublished - 2024
Event2024 International Workshop on Advanced Imaging Technology, IWAIT 2024 - Langkawi, Malaysia
Duration: 7 Jan 20248 Jan 2024

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume13164
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference2024 International Workshop on Advanced Imaging Technology, IWAIT 2024
Country/TerritoryMalaysia
CityLangkawi
Period7/01/248/01/24

Keywords

  • Biomarker analysis
  • Deep Learning
  • Multi-modal Learning
  • Multi-task Learning
  • Retinal OCT

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Fingerprint

Dive into the research topics of 'Deep Learning for Retina Structural Biomarker Classification Using OCT Images'. Together they form a unique fingerprint.

Cite this