Continuous protein recovery from whey using liquid-solid circulating fluidized bed ion-exchange extraction

Qingdao Lan, Amarjeet Bassi, Jing Xu Zhu, Argyrios Margaritis

Research output: Journal PublicationArticlepeer-review

64 Citations (Scopus)

Abstract

A liquid-solid circulating fluidized bed (LSCFB) continuous ion-exchange extraction system has been investigated for total protein recovery from whey solutions under various operating conditions. The effectiveness of a dynamic seal was evaluated between the riser and the downcomer, and the best conditions for the establishment of this seal were established. Start-up studies indicated that the system is robust and stable. Under optimal conditions, a productivity of 8.2 g of total protein removed per hour per kilogram of resin was achieved with a protein removal efficiency of 78.4%. However, higher overall protein recovery of up to 90% was also achieved under other conditions, with lower protein concentration in the effluent and a lower overall productivity.

Original languageEnglish
Pages (from-to)157-163
Number of pages7
JournalBiotechnology and Bioengineering
Volume78
Issue number2
DOIs
Publication statusPublished - 20 Apr 2002
Externally publishedYes

Keywords

  • Continuous ion exchange
  • Liquid-solid circulating fluidized bed
  • Whey proteins
  • Whole broth recovery

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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