Anti-neuroinflammatory activity of Elephantopus scaber L. via activation of Nrf2/HO-1 signaling and inhibition of p38 MAPK pathway in LPS-induced microglia BV-2 cells

Keyphrases

• Lipopolysaccharide 100%
• P38 MAPK Pathway 100%
• Anti-neuroinflammation 100%
• Nrf2-HO-1 100%
• Elephantopus Scaber 100%
• BV2 Cells 100%
• BV2 Microglia 100%
• Lipopolysaccharide-induced 100%
• Inflammatory Response 66%
• Adverse Effects 33%
• Safety Profile 33%
• Ethyl Acetate 33%
• Antioxidant Enzymes 33%
• Oral Administration 33%
• Interleukin-1β 33%
• Profile Analysis 33%
• Nutraceuticals 33%
• Enzyme Activity 33%
• Antioxidant Activity 33%
• Anti-inflammatory Activity 33%
• Scavenging Activity 33%
• Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) 33%
• Asteraceae Family 33%
• Inflammatory Mediators 33%
• NF-B 33%
• Inducible Nitric Oxide Synthase 33%
• Neuroinflammation 33%
• Cyclooxygenase-2 33%
• BV-2 33%
• Prostaglandin E2 33%
• Neuroinflammatory Disorders 33%
• Inflammatory Models 33%
• Heme oxygenase-1 (HO-1) 33%
• Folkloric Medicine 33%
• Catalase Enzyme 33%
• Scavenging Power 33%
• Microglial Cells 33%
• Induced Production 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Transcription Factor Nrf2 100%
• Lipopolysaccharide 100%
• Elephantopus Scaber 100%
• Inflammation 33%
• Disease 16%
• Mouse 16%
• Adverse Event 16%
• Tumor Necrosis Factor 16%
• Catalase 16%
• Antioxidant 16%
• Acetic Acid Ethyl Ester 16%
• Antioxidant Capacity 16%
• Anti-Inflammatory Drug 16%
• Asteraceae 16%
• Nervous System Inflammation 16%
• Nutraceutical 16%