A review on the application of carbon quantum dots on optical biosensors

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review


Carbon Quantum Dots (CQDs), also known as carbon dots or carbon nanodots, are zero-dimensional carbon nanomaterials composed of ultrafine, dispersed, quasi spherical, and carbon nanoparticles with a size below 10 nm. CQDs, as an emerging class of quantum dots (QDs) with good photoluminescence (PL) properties, simple and economical preparation and synthesis routes, inexpensive initial preparation materials, good water solubility, non-Toxicity, small particle sizes, tunable emission spectra, high fluorescence stability, good chemical properties, good biocompatibility, and ease of functionalization, have received widespread attention in recent years. Due to the fascinating chemical, optical, electrical and biological properties of CQDs, the sensitivity, detection limit and selectivity in multi-species detection of biosensors can be dramatically improved. Currently CQD-based biosensors have been applied to the detection of different species and scenarios, such as metal ions, acids, proteins, DNA and RNA, blood, drugs, vitamins and other compounds, and scenarios such as environmental gases and water quality monitoring, cellular imaging, drug labelling, and biomedical testing. It can be seen that CQDs-based biosensors are expected to be the leading sensors with high performance and high accuracy in different fields. This review presents the main methods reported in the scientific literature for the synthesis of CQDs, surface modifications, as well as describing different types of applications on optical biosensors based on the properties of CQDs and their working mechanisms.

Original languageEnglish
Title of host publicationAdvanced Fiber Laser Conference, AFL 2023
EditorsPu Zhou
ISBN (Electronic)9781510677661
Publication statusPublished - 2024
Event2023 Advanced Fiber Laser Conference, AFL 2023 - Shenzhen, China
Duration: 10 Nov 202312 Nov 2023

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


Conference2023 Advanced Fiber Laser Conference, AFL 2023


  • Applications
  • Biochemical detection
  • Biosensors
  • Carbon quantum dots
  • Medical detection
  • Optical fiber sensors
  • Optical sensing

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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