Research output per year
Research output per year
Search results
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2013
Sulforaphane can protect lens cells against oxidative stress: Implications for cataract prevention
Liu, H., Smith, A. J. O., Lott, M. C., Bao, Y., Bowater, R. P., Reddan, J. R. & Wormstone, I. M., 2013, In: Investigative Ophthalmology and Visual Science. 54, 8, p. 5236-5248 13 p.Research output: Journal Publication › Article › peer-review
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2014
An in vitro evaluation of the Anew Zephyr open-bag IOL in the prevention of posterior capsule opacification using a human capsular bag model
Eldred, J. A., Spalton, D. J. & Wormstone, I. M., 8 Sept 2014, In: Investigative Ophthalmology and Visual Science. 55, 11, p. 7057-7064 8 p.Research output: Journal Publication › Article › peer-review
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Effect of total lens epithelial cell destruction on intraocular lens fixation in the human capsular bag
Spalton, D. J., Russell, S. L., Evans-Gowing, R., Eldred, J. A. & Wormstone, I. M., Feb 2014, In: Journal of Cataract and Refractive Surgery. 40, 2, p. 306-312 7 p.Research output: Journal Publication › Article › peer-review
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Fibrotic modifications of the lens epithelium
Wormstone, I. M., Eldred, J. A. & Dawes, L. J., 1 Mar 2014, Lens Epithelium and Posterior Capsular Opacification. Springer Japan, Vol. 9784431543008. p. 143-158 16 p.Research output: Chapter in Book/Conference proceeding › Book Chapter › peer-review
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2015
Ku80 counters oxidative stress-induced DNA damage and cataract formation in the human lens
Smith, A. J. O., Ball, S. S. R., Manzar, K., Bowaterc, R. P. & Wormstone, I. M., 1 Dec 2015, In: Investigative Ophthalmology and Visual Science. 56, 13, p. 7868-7874 7 p.Research output: Journal Publication › Article › peer-review
Open Access -
2016
AGEs in human lens capsule promote the TGFβ2-mediated EMT of lens epithelial cells: Implications for age-associated fibrosis
Raghavan, C. T., Smuda, M., Smith, A. J. O., Howell, S., Smith, D. G., Singh, A., Gupta, P., Glomb, M. A., Wormstone, I. M. & Nagaraj, R. H., 1 Jun 2016, In: Aging Cell. 15, 3, p. 465-476 12 p.Research output: Journal Publication › Article › peer-review
Open Access -
Experimental models for posterior capsule opacification research
Wormstone, I. M. & Eldred, J. A., 1 Jan 2016, In: Experimental Eye Research. 142, p. 2-12 11 p.Research output: Journal Publication › Article › peer-review
Open Access -
Growth factor restriction impedes progression of wound healing following cataract surgery: Identification of VEGF as a putative therapeutic target
Eldred, J. A., McDonald, M., Wilkes, H. S., Spalton, D. J. & Wormstone, I. M., 14 Apr 2016, In: Scientific Reports. 6, 24453.Research output: Journal Publication › Article › peer-review
Open Access -
Improving the drug development process by reducing the impact of adverse events: The case of cataracts considered
Smith, A. F., Klotz, A. & Wormstone, I. M., Mar 2016, In: Drug Discovery Today. 21, 3, p. 510-516 7 p.Research output: Journal Publication › Review article › peer-review
Open Access -
PARP-1 inhibition influences the oxidative stress response of the human lens
Smith, A. J. O., Ball, S. S. R., Bowater, R. P. & Wormstone, I. M., 1 Aug 2016, In: Redox Biology. 8, p. 354-362 9 p.Research output: Journal Publication › Article › peer-review
Open Access -
2017
A direct comparison of linear and star-shaped poly(dimethylaminoethyl acrylate) polymers for polyplexation with DNA and cytotoxicity in cultured cell lines
Liao, X., Walden, G., Falcon, N. D., Donell, S., Raxworthy, M. J., Wormstone, M., Riley, G. P. & Saeed, A., 1 Feb 2017, In: European Polymer Journal. 87, p. 458-467 10 p.Research output: Journal Publication › Article › peer-review
Open Access -
Sulforaphane promotes ER stress, autophagy, and cell death: implications for cataract surgery
Liu, H., Smith, A. J., Ball, S. S., Bao, Y., Bowater, R. P., Wang, N. & Michael Wormstone, I., 1 May 2017, In: Journal of Molecular Medicine. 95, 5, p. 553-564 12 p.Research output: Journal Publication › Article › peer-review
Open Access -
2018
Chemopreventive activities of sulforaphane and its metabolites in human hepatoma HepG2 cells
Liu, P., Wang, W., Zhou, Z., Smith, A. J. O., Bowater, R. P., Wormstone, I. M., Chen, Y. & Bao, Y., 9 May 2018, In: Nutrients. 10, 5, 585.Research output: Journal Publication › Article › peer-review
Open Access -
Mutation profiles of congenital cataract genes in 21 northern chinese families
Zhang, X. H., Da Wang, J., Jia, H. Y., Zhang, J. S., Li, Y., Xiong, Y., Li, J., Li, X. X., Huang, Y., Zhu, G. Y., Rong, S. S., Wormstone, M. & Wan, X. H., 20 Jul 2018, In: Molecular Vision. 24, p. 471-477 7 p.Research output: Journal Publication › Article › peer-review
29 Citations (Scopus) -
2019
An in vitro human lens capsular bag model adopting a graded culture regime to assess putative impact of iols on pco formation
Eldred, J. A., Zheng, J., Chen, S. & Wormstone, I. M., 1 Jan 2019, In: Investigative Ophthalmology and Visual Science. 60, 1, p. 113-122 10 p.Research output: Journal Publication › Article › peer-review
Open Access -
Development and Validation of a Deep Learning System to Detect Glaucomatous Optic Neuropathy Using Fundus Photographs
Liu, H., Li, L., Wormstone, I. M., Qiao, C., Zhang, C., Liu, P., Li, S., Wang, H., Mou, D., Pang, R., Yang, D., Zangwill, L. M., Moghimi, S., Hou, H., Bowd, C., Jiang, L., Chen, Y., Hu, M., Xu, Y. & Kang, H. & 10 others, , Dec 2019, In: JAMA Ophthalmology. 137, 12, p. 1353-1360 8 p.Research output: Journal Publication › Article › peer-review
Open Access -
Resveratrol inhibits wound healing and lens fibrosis: A putative candidate for posterior capsule opacification prevention
Smith, A. J. O., Eldred, J. A. & Wormstone, I. M., 1 Sept 2019, In: Investigative Ophthalmology and Visual Science. 60, 12, p. 3863-3877 15 p.Research output: Journal Publication › Article › peer-review
Open Access -
2020
Aspirin inhibits TGFβ2-induced epithelial to mesenchymal transition of lens epithelial cells: Selective acetylation of K56 and K122 in histone H3
Nam, M. H., Smith, A. J. O., Pantcheva, M. B., Park, K. U., Brzezinski Iv, J. A., Galligan, J. J., Fritz, K., Wormstone, I. M. & Nagaraj, R. H., 8 Jan 2020, In: Biochemical Journal. 477, 1, p. 75-97 23 p.Research output: Journal Publication › Article › peer-review
Open Access -
The human capsular bag model of posterior capsule opacification
Wormstone, I. M., 1 Feb 2020, In: Eye. 34, 2, p. 225-231 7 p.Research output: Journal Publication › Article › peer-review
Open Access -
2021
Assessment of intraocular lens/capsular bag biomechanical interactions following cataract surgery in a human in vitro graded culture capsular bag model
Wormstone, I. M., Damm, N. B., Kelp, M. & Eldred, J. A., Apr 2021, In: Experimental Eye Research. 205, 108487.Research output: Journal Publication › Article › peer-review
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Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells
Huangfu, J., Hao, C., Wei, Z., Wormstone, I. M., Yan, H. & Fan, X., Apr 2021, In: Cell Death and Disease. 12, 4, 386.Research output: Journal Publication › Article › peer-review
Open Access -
Fluorofenidone inhibits the epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification
Wormstone, M., 2021, In: Arquivos Brasileiros de Oftalmologia. 84, 3, p. 303 1 p.Research output: Journal Publication › Article › peer-review
Open Access -
GSH levels serve as a biological redox switch regulating sulforaphane-induced cell fate in human lens cells
Huynh, T. P. N., Bowater, R. P., Bernuzzi, F., Saha, S. & Wormstone, I. M., Dec 2021, In: Investigative Ophthalmology and Visual Science. 62, 15, 2.Research output: Journal Publication › Article › peer-review
Open Access -
Interactions between polyphenolic antioxidants quercetin and naringenin dictate the distinctive redox-related chemical and biological behaviour of their mixtures
Baranowska, M., Koziara, Z., Suliborska, K., Chrzanowski, W., Wormstone, M., Namieśnik, J. & Bartoszek, A., Dec 2021, In: Scientific Reports. 11, 1, 12282.Research output: Journal Publication › Article › peer-review
Open Access -
Posterior capsule opacification: What's in the bag?
Wormstone, I. M., Wormstone, Y. M., Smith, A. J. O. & Eldred, J. A., May 2021, In: Progress in Retinal and Eye Research. 82, 100905.Research output: Journal Publication › Review article › peer-review
Open Access -
2022
27 Advancing the basic understanding and management of posterior capsule opacification following cataract surgery using human donor eyes
Wormstone, M., 1 Nov 2022, In: BMJ Open Ophthalmology. 7, p. A11-A12Research output: Journal Publication › Article › peer-review
Open Access -
2024
Lens capsule advanced glycation end products induce senescence in epithelial cells: Implications for secondary cataracts
Cooksley, G., Nam, M. H., Nahomi, R. B., Rankenberg, J., Smith, A. J. O., Wormstone, Y. M., Wormstone, I. M. & Nagaraj, R. H., Oct 2024, In: Aging Cell. 23, 10, e14249.Research output: Journal Publication › Article › peer-review
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Stereolithographic Rapid Prototyping of Clear, Foldable, Non-Refractive Intraocular Lens Designs: A Proof-of-Concept Study
Hidalgo-Alvarez, V., Falcon, N. D., Eldred, J., Wormstone, M. & Saeed, A., 2024, In: Current Eye Research. 49, 8, p. 843-852 10 p.Research output: Journal Publication › Article › peer-review
Open Access -
2025
A single‑cell transcriptomic atlas of human lens epithelium: identification and functional insights into lens stem/progenitor cells
Gu, Y., Chen, L., Chen, S., Wu, Y., Hao, S., Sheng, F., YUAN, J., Qin, Z., Wu, D., Han, Y., Yao, Z., Chen, Z., Wormstone, M., Yu, Y., Qian, J., Fu, Q. & Yao, K., 1 Jul 2025, In: Stem Cell Research and Therapy.Research output: Journal Publication › Article › peer-review
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