TY - GEN
T1 - Towards automatic detection of age-related macular degeneration in retinal fundus images
AU - Liang, Ziyang
AU - Wong, Damon W.K.
AU - Liu, Jiang
AU - Chan, Kap Luk
AU - Wong, Tien Yin
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2010
Y1 - 2010
N2 - Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. The disease is highly associated with age, and becoming increasingly prevalent in our aging societies. Drusen is a pathological feature that is well-associated with AMD. In this paper, we present a method of detecting drusen in retinal fundus images. The method first determines the location of the macula, which is used as a landmark for a clinical drusen grading overlay. Subsequently, regions of drusen are identified though a maximal region-based pixel intensity approach via RGB and HSV channels. Methods of reducing the effect of retinal and choroidal vessels are also described. The system is tested on a sample set of 16 fundus images from a clinical study, with half having drusen. Experiments on the results show a sensitivity and specificity of 0.75 on the test image set.
AB - Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. The disease is highly associated with age, and becoming increasingly prevalent in our aging societies. Drusen is a pathological feature that is well-associated with AMD. In this paper, we present a method of detecting drusen in retinal fundus images. The method first determines the location of the macula, which is used as a landmark for a clinical drusen grading overlay. Subsequently, regions of drusen are identified though a maximal region-based pixel intensity approach via RGB and HSV channels. Methods of reducing the effect of retinal and choroidal vessels are also described. The system is tested on a sample set of 16 fundus images from a clinical study, with half having drusen. Experiments on the results show a sensitivity and specificity of 0.75 on the test image set.
UR - http://www.scopus.com/inward/record.url?scp=78650805723&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2010.5627289
DO - 10.1109/IEMBS.2010.5627289
M3 - Conference contribution
C2 - 21096627
AN - SCOPUS:78650805723
SN - 9781424441235
T3 - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
SP - 4100
EP - 4103
BT - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
T2 - 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Y2 - 31 August 2010 through 4 September 2010
ER -
