Systems biology approach in hypertension research

Christian Delles, Husi Holger

Research output: Chapter in Book/Conference proceedingBook Chapterpeer-review

6 Citations (Scopus)

Abstract

Systems biology is an approach to study all genes, gene transcripts, proteins, metabolites, and their interactions in specific cells, tissues, organs, or the whole organism. It is based on data derived from high-throughput analytical technologies and bioinformatics tools to analyze these data, and aims to understand the whole system rather than individual aspects of it. Systems biology can be applied to virtually all conditions and diseases and therefore also to hypertension and its underlying vascular disorders. Unlike other methods in this book there is no clear-cut protocol to explain a systems biology approach. We will instead outline some of the most important and common steps in the generation and analysis of systems biology data.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages69-79
Number of pages11
DOIs
Publication statusPublished - 2017
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1527
ISSN (Print)1064-3745

Keywords

  • Bioinformatics
  • Data integration
  • Genomics
  • Metabolomics
  • Pathway analysis
  • Proteomics
  • Systems biology
  • Transcriptomics

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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