TY - GEN
T1 - Synthesis of Hydroxyapatite Scaffolds via 3D-Printing and Sintering for Bone Regeneration
AU - Soh, Ryan Zhe Hse
AU - Cheah, Kean How
AU - Wong, Voon Loong
AU - Lim, Siew Shee
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.
PY - 2024
Y1 - 2024
N2 - 3D-printing proves to be a promising bone scaffold production technology due to its ability to control scaffold geometry with high accuracy. This paper entails the use of calcium phosphate blended with commercial polymer resin at different weight per cents (10, 15, 20, 25 and 30) to be 3D-printed and sintered at 900, 1000 and 1100 °C. The sintered scaffolds were characterised using X-ray diffraction, stereo microscopy, field emission scanning electron microscopy, energy dispersive spectroscopy, compressive modulus tests and porosity tests. Results indicated that average pore size, crystallinity, porosity and compressive modulus of the scaffolds were successfully controlled using 3D-printing with regards to emulating properties of cancellous bone. Among these scaffolds, scaffolds of 30 wt.% hydroxyapatite sintered at 1100 °C showed the optimum physical and mechanical properties and can be a potential alternative for bone regeneration.
AB - 3D-printing proves to be a promising bone scaffold production technology due to its ability to control scaffold geometry with high accuracy. This paper entails the use of calcium phosphate blended with commercial polymer resin at different weight per cents (10, 15, 20, 25 and 30) to be 3D-printed and sintered at 900, 1000 and 1100 °C. The sintered scaffolds were characterised using X-ray diffraction, stereo microscopy, field emission scanning electron microscopy, energy dispersive spectroscopy, compressive modulus tests and porosity tests. Results indicated that average pore size, crystallinity, porosity and compressive modulus of the scaffolds were successfully controlled using 3D-printing with regards to emulating properties of cancellous bone. Among these scaffolds, scaffolds of 30 wt.% hydroxyapatite sintered at 1100 °C showed the optimum physical and mechanical properties and can be a potential alternative for bone regeneration.
KW - 3D-printing
KW - Fusion of particles
KW - Gyroid structure
UR - http://www.scopus.com/inward/record.url?scp=85207684726&partnerID=8YFLogxK
U2 - 10.1007/978-981-97-1920-4_29
DO - 10.1007/978-981-97-1920-4_29
M3 - Conference contribution
AN - SCOPUS:85207684726
SN - 9789819721108
T3 - Lecture Notes in Bioengineering
SP - 301
EP - 309
BT - Proceedings of the Annual Congress of the Asia-Pacific Society for Artificial Organs - APSAO
A2 - Mohamed Mokhtarudin, Mohd Jamil
A2 - Ahmad Bakir, Azam
A2 - Stephens, Andrew
A2 - Sulaiman, Nadiah
PB - Springer Science and Business Media Deutschland GmbH
T2 - Annual Congress of the Asia-Pacific Society for Artificial Organs, APSAO 2023
Y2 - 25 September 2023 through 26 September 2023
ER -