Prior-SSL: A Thickness Distribution Prior and Uncertainty Guided Semi-supervised Learning Method for Choroidal Segmentation in OCT Images

Huihong Zhang, Xiaoqing Zhang, Yinlin Zhang, Risa Higashita, Jiang Liu

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

Choroid structure is crucial for the diagnosis of ocular diseases, and deep supervised learning (SL) techniques have been widely applied to segment the choroidal structure based on OCT images. However, SL requires massive annotated data, which is difficult to obtain. Researchers have explored semi-supervised learning (SSL) methods based on consistency regularization and achieved strong performance. However, these methods suffer from heavy computational burdens and introduce noise that hinders the training process. To address these issues, we propose a thickness distribution prior and uncertainty aware pseudo-label selection SSL framework (Prior-SSL) for OCT choroidal segmentation. Specifically, we compute the instance-level uncertainty of the pseudo-label candidate, which significantly reduces the computational burden of uncertainty estimation. In addition, we consider the physiological characteristics of the choroid, explore the choroidal thickness distribution as prior knowledge in the pseudo-label selection procedure, and thereby obtain more reliable and accurate pseudo-labels. Finally, these two branches are combined via a Modified AND-Gate (MAG) to assign confidence levels to pseudo-label candidates. We achieve state-of-the-art performance for the choroidal segmentation task on the GOALS and NIDEK OCT datasets. Ablation studies verify the effectiveness of the Prior-SSL in selecting high-quality pseudo-labels.

Original languageEnglish
Title of host publicationArtificial Neural Networks and Machine Learning – ICANN 2023 - 32nd International Conference on Artificial Neural Networks, Proceedings
EditorsLazaros Iliadis, Antonios Papaleonidas, Plamen Angelov, Chrisina Jayne
PublisherSpringer Science and Business Media Deutschland GmbH
Pages570-581
Number of pages12
ISBN (Print)9783031442094
DOIs
Publication statusPublished - 2023
Externally publishedYes
Event32nd International Conference on Artificial Neural Networks, ICANN 2023 - Heraklion, Greece
Duration: 26 Sept 202329 Sept 2023

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume14255 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference32nd International Conference on Artificial Neural Networks, ICANN 2023
Country/TerritoryGreece
CityHeraklion
Period26/09/2329/09/23

Keywords

  • OCT image
  • choroidal segmentation
  • prior knowledge
  • pseudo-label
  • semi-supervised learning (SSL)

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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