Picosecond transient infrared study of the ultrafast deactivation processes of electronically excited B-DNA and Z-DNA forms of [poly(dG-dC)]2

Gerard W. Doorley; David A. McGovern; Michael W. George; Michael Towrie; Anthony W. Parker; John M. Kelly; Susan J. Quinn

doi:10.1002/anie.200803904

Picosecond transient infrared study of the ultrafast deactivation processes of electronically excited B-DNA and Z-DNA forms of [poly(dG-dC)]₂

Gerard W. Doorley, David A. McGovern, Michael W. George, Michael Towrie, Anthony W. Parker, John M. Kelly, Susan J. Quinn

Research output: Journal Publication › Article › peer-review

45 Citations (Scopus)

Abstract

(Graph Presented) Very fast: UV excitation of the right-handed B form or the left-handed Z form of [poly(dG-dC)]₂ results in transient IR absorption bands that remain long after the ¹ππ* state is predicted to have decayed (see picture). A biexponential decay is observed for B-DNA, which is assigned to the vibrationally excited ground state and the ¹n_Nπ* state. The decay of Z-DNA is dominated by single-exponential decay, which is assigned to an exciplex state.

Original language	English
Pages (from-to)	123-127
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	1
DOIs	https://doi.org/10.1002/anie.200803904
Publication status	Published - 2009
Externally published	Yes

Keywords

DNA
IR spectroscopy
Nucleotides
Time-resolved spectroscopy
Ultrafast processes

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1002/anie.200803904

Cite this

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title = "Picosecond transient infrared study of the ultrafast deactivation processes of electronically excited B-DNA and Z-DNA forms of [poly(dG-dC)]2",

abstract = "(Graph Presented) Very fast: UV excitation of the right-handed B form or the left-handed Z form of [poly(dG-dC)]2 results in transient IR absorption bands that remain long after the 1ππ* state is predicted to have decayed (see picture). A biexponential decay is observed for B-DNA, which is assigned to the vibrationally excited ground state and the 1nNπ* state. The decay of Z-DNA is dominated by single-exponential decay, which is assigned to an exciplex state.",

keywords = "DNA, IR spectroscopy, Nucleotides, Time-resolved spectroscopy, Ultrafast processes",

author = "Doorley, {Gerard W.} and McGovern, {David A.} and George, {Michael W.} and Michael Towrie and Parker, {Anthony W.} and Kelly, {John M.} and Quinn, {Susan J.}",

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language = "English",

volume = "48",

pages = "123--127",

journal = "Angewandte Chemie - International Edition",

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T1 - Picosecond transient infrared study of the ultrafast deactivation processes of electronically excited B-DNA and Z-DNA forms of [poly(dG-dC)]2

AU - Doorley, Gerard W.

AU - McGovern, David A.

AU - George, Michael W.

AU - Towrie, Michael

AU - Parker, Anthony W.

AU - Kelly, John M.

AU - Quinn, Susan J.

PY - 2009

Y1 - 2009

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AB - (Graph Presented) Very fast: UV excitation of the right-handed B form or the left-handed Z form of [poly(dG-dC)]2 results in transient IR absorption bands that remain long after the 1ππ* state is predicted to have decayed (see picture). A biexponential decay is observed for B-DNA, which is assigned to the vibrationally excited ground state and the 1nNπ* state. The decay of Z-DNA is dominated by single-exponential decay, which is assigned to an exciplex state.

KW - DNA

KW - IR spectroscopy

KW - Nucleotides

KW - Time-resolved spectroscopy

KW - Ultrafast processes

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