Perspectives of hyperpolarized noble gas MRI beyond 3He

David M.L. Lilburn; Galina E. Pavlovskaya; Thomas Meersmann

doi:10.1016/j.jmr.2012.11.014

Perspectives of hyperpolarized noble gas MRI beyond ³He

David M.L. Lilburn, Galina E. Pavlovskaya, Thomas Meersmann

Research output: Journal Publication › Article › peer-review

79 Citations (Scopus)

Abstract

Nuclear Magnetic Resonance (NMR) studies with hyperpolarized (hp) noble gases are at an exciting interface between physics, chemistry, materials science and biomedical sciences. This paper intends to provide a brief overview and outlook of magnetic resonance imaging (MRI) with hp noble gases other than hp ³He. A particular focus are the many intriguing experiments with ¹²⁹Xe, some of which have already matured to useful MRI protocols, while others display high potential for future MRI applications. Quite naturally for MRI applications the major usage so far has been for biomedical research but perspectives for engineering and materials science studies are also provided. In addition, the prospects for surface sensitive contrast with hp ⁸³Kr MRI is discussed.

Original language	English
Pages (from-to)	173-186
Number of pages	14
Journal	Journal of Magnetic Resonance
Volume	229
DOIs	https://doi.org/10.1016/j.jmr.2012.11.014
Publication status	Published - Apr 2013
Externally published	Yes

Keywords

Xe
Kr
Biosensor
Chemical shift selective
Combustion
Diffusion
Flow
Gas phase
Hyperpolarization
Hyperpolarized
Kr-83
Krypton-83
Lung pathology
Molecular imaging
MRI contrast
NMR spectroscopy
Nuclear electric quadrupole moment
Porous materials
Pulmonary MRI
Quadrupolar relaxation
Remote detection
Spin polarization
Spin-exchange optical pumping
Surface sensitive
Transport weighted
Xe-129
Xenon-129

ASJC Scopus subject areas

Biophysics
Biochemistry
Nuclear and High Energy Physics
Condensed Matter Physics

Access to Document

10.1016/j.jmr.2012.11.014

Cite this

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title = "Perspectives of hyperpolarized noble gas MRI beyond 3He",

abstract = "Nuclear Magnetic Resonance (NMR) studies with hyperpolarized (hp) noble gases are at an exciting interface between physics, chemistry, materials science and biomedical sciences. This paper intends to provide a brief overview and outlook of magnetic resonance imaging (MRI) with hp noble gases other than hp 3He. A particular focus are the many intriguing experiments with 129Xe, some of which have already matured to useful MRI protocols, while others display high potential for future MRI applications. Quite naturally for MRI applications the major usage so far has been for biomedical research but perspectives for engineering and materials science studies are also provided. In addition, the prospects for surface sensitive contrast with hp 83Kr MRI is discussed.",

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author = "Lilburn, {David M.L.} and Pavlovskaya, {Galina E.} and Thomas Meersmann",

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AU - Pavlovskaya, Galina E.

AU - Meersmann, Thomas

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