Functional prediction of snake neurotoxins

Seng Hong Seah; Chee Keong Kwoh; Vladimir Brusic; Meena Kishore Sakharkar; Geok See Ng

doi:10.1109/ICARCV.2006.345470

Functional prediction of snake neurotoxins

Seng Hong Seah, Chee Keong Kwoh, Vladimir Brusic, Meena Kishore Sakharkar, Geok See Ng

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

Abstract

Snake neurotoxins are important experimental tool in pharmacological research. Over the years, the number of snake neurotoxin sequences identified is increasing at a very fast pace. However, only a small portion of them are experimentally characterized from more than 200,000 variants estimated to exist in nature. In this paper, we report a systematic functional analysis on snake neurotoxins using a statistical machine learning method - nearest neighbour approach for functional prediction together with a set of rules. Based on this method we built a highly accurate functional prediction tool for putative annotation for snake neurotoxins.

Original language	English
Title of host publication	9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06
DOIs	https://doi.org/10.1109/ICARCV.2006.345470
Publication status	Published - 2006
Externally published	Yes
Event	9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06 - Singapore, Singapore Duration: 5 Dec 2006 → 8 Dec 2006

Publication series

Name	9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06

Conference

Conference	9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06
Country/Territory	Singapore
City	Singapore
Period	5/12/06 → 8/12/06

Keywords

Nearest neighbour
Prediction
Snake neurotoxins

ASJC Scopus subject areas

Computer Science Applications
Computer Vision and Pattern Recognition
Control and Systems Engineering

Access to Document

10.1109/ICARCV.2006.345470

Cite this

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title = "Functional prediction of snake neurotoxins",

abstract = "Snake neurotoxins are important experimental tool in pharmacological research. Over the years, the number of snake neurotoxin sequences identified is increasing at a very fast pace. However, only a small portion of them are experimentally characterized from more than 200,000 variants estimated to exist in nature. In this paper, we report a systematic functional analysis on snake neurotoxins using a statistical machine learning method - nearest neighbour approach for functional prediction together with a set of rules. Based on this method we built a highly accurate functional prediction tool for putative annotation for snake neurotoxins.",

keywords = "Nearest neighbour, Prediction, Snake neurotoxins",

author = "Seah, {Seng Hong} and Kwoh, {Chee Keong} and Vladimir Brusic and Sakharkar, {Meena Kishore} and Ng, {Geok See}",

year = "2006",

doi = "10.1109/ICARCV.2006.345470",

language = "English",

isbn = "1424403421",

series = "9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06",

booktitle = "9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06",

note = "9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06 ; Conference date: 05-12-2006 Through 08-12-2006",

}

Seah, SH, Kwoh, CK, Brusic, V, Sakharkar, MK & Ng, GS 2006, Functional prediction of snake neurotoxins. in 9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06., 4150399, 9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06, 9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06, Singapore, Singapore, 5/12/06. https://doi.org/10.1109/ICARCV.2006.345470

Functional prediction of snake neurotoxins. / Seah, Seng Hong; Kwoh, Chee Keong; Brusic, Vladimir et al.
9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06. 2006. 4150399 (9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06).

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Functional prediction of snake neurotoxins

AU - Seah, Seng Hong

AU - Kwoh, Chee Keong

AU - Brusic, Vladimir

AU - Sakharkar, Meena Kishore

AU - Ng, Geok See

PY - 2006

Y1 - 2006

N2 - Snake neurotoxins are important experimental tool in pharmacological research. Over the years, the number of snake neurotoxin sequences identified is increasing at a very fast pace. However, only a small portion of them are experimentally characterized from more than 200,000 variants estimated to exist in nature. In this paper, we report a systematic functional analysis on snake neurotoxins using a statistical machine learning method - nearest neighbour approach for functional prediction together with a set of rules. Based on this method we built a highly accurate functional prediction tool for putative annotation for snake neurotoxins.

AB - Snake neurotoxins are important experimental tool in pharmacological research. Over the years, the number of snake neurotoxin sequences identified is increasing at a very fast pace. However, only a small portion of them are experimentally characterized from more than 200,000 variants estimated to exist in nature. In this paper, we report a systematic functional analysis on snake neurotoxins using a statistical machine learning method - nearest neighbour approach for functional prediction together with a set of rules. Based on this method we built a highly accurate functional prediction tool for putative annotation for snake neurotoxins.

KW - Nearest neighbour

KW - Prediction

KW - Snake neurotoxins

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U2 - 10.1109/ICARCV.2006.345470

DO - 10.1109/ICARCV.2006.345470

M3 - Conference contribution

AN - SCOPUS:34547187700

SN - 1424403421

SN - 9781424403424

T3 - 9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06

BT - 9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06

T2 - 9th International Conference on Control, Automation, Robotics and Vision, 2006, ICARCV '06

Y2 - 5 December 2006 through 8 December 2006

ER -

Functional prediction of snake neurotoxins

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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