Effects of Mediterranean diets and nutrigenomics on cardiovascular health

Saad Bakrim, Sara Aboulaghras, Tarik Aanniz, Taoufiq Benali, Nasreddine El Omari, Mohamed El-Shazly, Learn Han Lee, Syed Khalid Mustafa, Nargis Sahib, Maksim Rebezov, Mohammad Ali Shariati, Jose M. Lorenzo, Abdelhakim Bouyahya

Research output: Journal PublicationReview articlepeer-review

3 Citations (Scopus)

Abstract

The field of nutrigenomics studies the interaction between nutrition and genetics, and how certain dietary patterns can impact gene expression and overall health. The Mediterranean diet (MedDiet), characterized by a high intake of fruits, vegetables, whole grains, and healthy fats, has been linked to better cardiovascular health (CVH) outcomes. This review summarizes the current state of research on the effects of nutrigenomics and MedDiet on cardiovascular health. Results suggest that MedDiet, through its impact on gene expression, can positively influence CVH markers such as blood pressure, lipid profile, and inflammation. However, more research is needed to fully understand the complex interactions between genetics, nutrition, and CVH, and to determine the optimal dietary patterns for individualized care. The aim of this scientific review is to evaluate the current evidence on the effects of nutrigenomics and MedDiet on cardiovascular health. The review summarizes the available studies that have investigated the relationship between nutrition, genetics, and cardiovascular health, and explores the mechanisms by which certain dietary patterns can impact CVH outcomes. The review focuses on the effects of MedDiet, a dietary pattern that is rich in whole foods and healthy fats, and its potential to positively influence CVH through its impact on gene expression. The review highlights the limitations of current research and the need for further studies to fully understand the complex interplay between nutrition, genetics, and cardiovascular health.

Original languageEnglish
JournalCritical Reviews in Food Science and Nutrition
DOIs
Publication statusAccepted/In press - 2023
Externally publishedYes

Keywords

  • Cardiovascular health
  • epigenetic
  • genetics
  • healthy fats
  • nutrition

ASJC Scopus subject areas

  • Food Science
  • Industrial and Manufacturing Engineering

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