Design of a Si photonic wire "lab on a chip" arrayed biosensor

Yaping Zhang

doi:10.1109/SOPO.2012.6270970

Design of a Si photonic wire "lab on a chip" arrayed biosensor

Yaping Zhang

Department of Electrical and Electronic Engineering

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

Abstract

This paper presents a design for a label free Si photonic wire "lab on a chip" arrayed biosensor with 8 sensing and 8 reference channels. It provides an advanced means for the label free detection of target molecules, for affinity binding analysis and for the time domain real-time monitoring and parallel detection of solutions, gases, or reactions near the sensing channel surface. The sensitivity of detection of the device is at the highest level among all the other methods, which is at least 10-100 times more sensitive than that of currently commercial available biosensor devices and instruments. The fabrication of the device is compatible with well-established semiconductor fabrication technologies. The device is able to be monolithically integrated with CMOS electronics, and combined with microfluidics.

Original language	English
Title of host publication	2012 Symposium on Photonics and Optoelectronics, SOPO 2012
DOIs	https://doi.org/10.1109/SOPO.2012.6270970
Publication status	Published - 2012
Event	2012 International Symposium on Photonics and Optoelectronics, SOPO 2012 - Shanghai, China Duration: 21 May 2012 → 23 May 2012

Publication series

Name	2012 Symposium on Photonics and Optoelectronics, SOPO 2012

Conference

Conference	2012 International Symposium on Photonics and Optoelectronics, SOPO 2012
Country/Territory	China
City	Shanghai
Period	21/05/12 → 23/05/12

Keywords

SOI
biosensor
lab on a chip
label free detection
microfluidics
parallel detection
silicon photonic wire
time domain real time detection

ASJC Scopus subject areas

Electrical and Electronic Engineering

Access to Document

10.1109/SOPO.2012.6270970

Cite this

@inproceedings{6b4a8ef12eec488690934424c7689348,

title = "Design of a Si photonic wire {"}lab on a chip{"} arrayed biosensor",

abstract = "This paper presents a design for a label free Si photonic wire {"}lab on a chip{"} arrayed biosensor with 8 sensing and 8 reference channels. It provides an advanced means for the label free detection of target molecules, for affinity binding analysis and for the time domain real-time monitoring and parallel detection of solutions, gases, or reactions near the sensing channel surface. The sensitivity of detection of the device is at the highest level among all the other methods, which is at least 10-100 times more sensitive than that of currently commercial available biosensor devices and instruments. The fabrication of the device is compatible with well-established semiconductor fabrication technologies. The device is able to be monolithically integrated with CMOS electronics, and combined with microfluidics.",

keywords = "SOI, biosensor, lab on a chip, label free detection, microfluidics, parallel detection, silicon photonic wire, time domain real time detection",

author = "Yaping Zhang",

year = "2012",

doi = "10.1109/SOPO.2012.6270970",

language = "English",

isbn = "9781457709111",

series = "2012 Symposium on Photonics and Optoelectronics, SOPO 2012",

booktitle = "2012 Symposium on Photonics and Optoelectronics, SOPO 2012",

}

TY - GEN

T1 - Design of a Si photonic wire "lab on a chip" arrayed biosensor

AU - Zhang, Yaping

PY - 2012

Y1 - 2012

N2 - This paper presents a design for a label free Si photonic wire "lab on a chip" arrayed biosensor with 8 sensing and 8 reference channels. It provides an advanced means for the label free detection of target molecules, for affinity binding analysis and for the time domain real-time monitoring and parallel detection of solutions, gases, or reactions near the sensing channel surface. The sensitivity of detection of the device is at the highest level among all the other methods, which is at least 10-100 times more sensitive than that of currently commercial available biosensor devices and instruments. The fabrication of the device is compatible with well-established semiconductor fabrication technologies. The device is able to be monolithically integrated with CMOS electronics, and combined with microfluidics.

AB - This paper presents a design for a label free Si photonic wire "lab on a chip" arrayed biosensor with 8 sensing and 8 reference channels. It provides an advanced means for the label free detection of target molecules, for affinity binding analysis and for the time domain real-time monitoring and parallel detection of solutions, gases, or reactions near the sensing channel surface. The sensitivity of detection of the device is at the highest level among all the other methods, which is at least 10-100 times more sensitive than that of currently commercial available biosensor devices and instruments. The fabrication of the device is compatible with well-established semiconductor fabrication technologies. The device is able to be monolithically integrated with CMOS electronics, and combined with microfluidics.

KW - SOI

KW - biosensor

KW - lab on a chip

KW - label free detection

KW - microfluidics

KW - parallel detection

KW - silicon photonic wire

KW - time domain real time detection

UR - http://www.scopus.com/inward/record.url?scp=84867542192&partnerID=8YFLogxK

U2 - 10.1109/SOPO.2012.6270970

DO - 10.1109/SOPO.2012.6270970

M3 - Conference contribution

AN - SCOPUS:84867542192

SN - 9781457709111

T3 - 2012 Symposium on Photonics and Optoelectronics, SOPO 2012

BT - 2012 Symposium on Photonics and Optoelectronics, SOPO 2012

T2 - 2012 International Symposium on Photonics and Optoelectronics, SOPO 2012

Y2 - 21 May 2012 through 23 May 2012

ER -

Design of a Si photonic wire "lab on a chip" arrayed biosensor

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this