Computational tools for the study of allergens

V. Brusic; N. Petrovsky; S. M. Gendel; M. Millot; O. Gigonzac; S. J. Stelman

doi:10.1034/j.1398-9995.2003.00224.x

Computational tools for the study of allergens

V. Brusic, N. Petrovsky, S. M. Gendel, M. Millot, O. Gigonzac, S. J. Stelman

Research output: Journal Publication › Review article › peer-review

46 Citations (Scopus)

Abstract

Allergy is a major cause of morbidity worldwide. The number of characterized allergens and related information is increasing rapidly creating demands for advanced information storage, retrieval and analysis. Bioinformatics provides useful tools for analysing allergens and these are complementary to traditional laboratory techniques for the study of allergens. Specific applications include structural analysis of allergens, identification of B- and T-cell epitopes, assessment of allergenicity and cross-reactivity, and genome analysis. In this paper, the most important bioinformatic tools and methods with relevance to the study of allergy have been reviewed.

Original language	English
Pages (from-to)	1083-1092
Number of pages	10
Journal	Allergy: European Journal of Allergy and Clinical Immunology
Volume	58
Issue number	11
DOIs	https://doi.org/10.1034/j.1398-9995.2003.00224.x
Publication status	Published - Nov 2003
Externally published	Yes

Keywords

Allergen
Molecular modelling
Prediction of allergenicity
Prediction of cross-reactivity
Sequence analysis

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1034/j.1398-9995.2003.00224.x

Cite this

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abstract = "Allergy is a major cause of morbidity worldwide. The number of characterized allergens and related information is increasing rapidly creating demands for advanced information storage, retrieval and analysis. Bioinformatics provides useful tools for analysing allergens and these are complementary to traditional laboratory techniques for the study of allergens. Specific applications include structural analysis of allergens, identification of B- and T-cell epitopes, assessment of allergenicity and cross-reactivity, and genome analysis. In this paper, the most important bioinformatic tools and methods with relevance to the study of allergy have been reviewed.",

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AU - Brusic, V.

AU - Petrovsky, N.

AU - Gendel, S. M.

AU - Millot, M.

AU - Gigonzac, O.

AU - Stelman, S. J.

PY - 2003/11

Y1 - 2003/11

N2 - Allergy is a major cause of morbidity worldwide. The number of characterized allergens and related information is increasing rapidly creating demands for advanced information storage, retrieval and analysis. Bioinformatics provides useful tools for analysing allergens and these are complementary to traditional laboratory techniques for the study of allergens. Specific applications include structural analysis of allergens, identification of B- and T-cell epitopes, assessment of allergenicity and cross-reactivity, and genome analysis. In this paper, the most important bioinformatic tools and methods with relevance to the study of allergy have been reviewed.

AB - Allergy is a major cause of morbidity worldwide. The number of characterized allergens and related information is increasing rapidly creating demands for advanced information storage, retrieval and analysis. Bioinformatics provides useful tools for analysing allergens and these are complementary to traditional laboratory techniques for the study of allergens. Specific applications include structural analysis of allergens, identification of B- and T-cell epitopes, assessment of allergenicity and cross-reactivity, and genome analysis. In this paper, the most important bioinformatic tools and methods with relevance to the study of allergy have been reviewed.

KW - Allergen

KW - Molecular modelling

KW - Prediction of allergenicity

KW - Prediction of cross-reactivity

KW - Sequence analysis

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DO - 10.1034/j.1398-9995.2003.00224.x

M3 - Review article

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AN - SCOPUS:0242556415

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JF - Allergy: European Journal of Allergy and Clinical Immunology

IS - 11

ER -

Computational tools for the study of allergens

Abstract

Keywords

ASJC Scopus subject areas

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