Synthesis and characterization of cinnamic acid conjugated N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride derivatives: A hybrid flocculant with antibacterial activity

Min Wang, Lin Yue, Sobia Niazi, Imran Mahmood Khan, Yin Zhang, Zhouping Wang

Research output: Journal PublicationArticlepeer-review

16 Citations (Scopus)

Abstract

The modified natural biopolymers, recognized as environmentally friendly flocculants, are gaining tremendous attention in the field of water treatment. In this study, a novel hybrid flocculant with antibacterial activity, cinnamic acid (CA) conjugated N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride (HTCC) derivative (HTCC-CA), was prepared via quaternary ammonium and amide reactions. The characterization, flocculation, and antibacterial activities were carried out to access the structural properties and potential application. The results of UV–vis, FT-TR, and 1H NMR confirmed the successful synthesis of HTCC-CA1-3 derivatives. XRD and TGA revealed the lower crystallinity and thermal stability of HTCC-CA1-3 derivatives than chitosan (CS). Bacterial flocculation and antibacterial tests indicated the excellent flocculation effect of HTCC-CA1-3 derivatives and showed high antibacterial activity for Escherichia coli suspension. Moreover, the mechanism of action of the derivatives was investigated via zeta potential measurements and scanning electron microscope, which can be summed up as the effective interaction between charges. The results proved that HTCC-CA derivatives are promising agents for wastewater treatment.

Original languageEnglish
Pages (from-to)886-895
Number of pages10
JournalInternational Journal of Biological Macromolecules
Volume206
DOIs
Publication statusPublished - 1 May 2022
Externally publishedYes

Keywords

  • Antibacterial activity
  • Chemical modification
  • Chitosan
  • Cinnamic acid
  • Flocculation

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry
  • Molecular Biology

Fingerprint

Dive into the research topics of 'Synthesis and characterization of cinnamic acid conjugated N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride derivatives: A hybrid flocculant with antibacterial activity'. Together they form a unique fingerprint.

Cite this