Self-Powered Electrowetting Valve for Instantaneous and Simultaneous Actuation of Paper-Based Microfluidic Assays

Zi Hao Guo, Yu Cui Jiao, Hai Lu Wang, Chen Zhang, Fei Liang, Jin Long Liu, Hai Dong Yu, Cheng Ming Li, Guang Zhu, Zhong Lin Wang

Research output: Journal PublicationArticlepeer-review

15 Citations (Scopus)

Abstract

In this work, a self-powered electrowetting valve (SPEV) driven by an energy-harvesting triboelectric nanogenerator (TENG) is reported. The TENG (5 × 5 cm 2 ) can produce an open-circuit voltage of 380 V by applying a mechanical stimulus, which is much higher than the actuation voltage of the SPEV (130 V). Once actuated, the electrowetting valve can be instantly switched on at a response time of 0.18 s, allowing liquid reagent to flow through the valve. The SPEV can be used for simultaneous addition of multiple reagents in an enzyme-linked immunosorbent assay on a paper-based microfluidic analytical device (µPAD). This assay involves a chromogenic reaction that achieves effective detection of alpha-fetoprotein, a critical tumor marker for early diagnosis of liver cancer. The SPEV reported in this work can be potentially used in other complex multiprocedure µPADs, which will potentially enable portable, accessible, and cost-effective assays for early diagnosis, food safety, pollution detection, etc.

Original languageEnglish
Article number1808974
JournalAdvanced Functional Materials
Volume29
Issue number15
DOIs
Publication statusPublished - 11 Apr 2019

Keywords

  • electrowetting
  • paper-based microfluidic analytical devices
  • self-powered
  • triboelectric nanogenerator

ASJC Scopus subject areas

  • Chemistry (all)
  • Materials Science (all)
  • Condensed Matter Physics

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