TY - GEN
T1 - NUMERICAL AND EXPERIMENTAL STUDY ON FLUID-STRUCTURE INTERACTIONS IN THE OSCILLATING FLOW IN A MICROFLUIDIC DEVICE
AU - Hou, Tuo
AU - Wang, Jing
AU - Ren, Yong
N1 - Publisher Copyright:
© 2024 by ASME.
PY - 2024
Y1 - 2024
N2 - Microcapsules, sized 1-1000 μm, offer a core-shell structure for encapsulating diverse substances, crucial in drug delivery and various applications. This work explores microcapsule deformation in microchannels with oscillating walls, utilizing a front-tracking-based 2D membrane model for Poiseuille flow. The microcapsules are created using a needle-based device, and the shell is made of a high-precision PLA bio-based resin, encapsulating the liquid core. The microcapsules are subjected to parallel plate compression experiments to assess their mechanical properties. Numerical simulations of the compression experiment are conducted, showing stress distribution within the capsule shell. A front-tracking-based 2D membrane model was applied to investigate the deformation of the microcapsule with a thin membrane shell and a liquid core in the Poiseuille flow. The microcapsules are further tested in an oscillating microchannel under different frequencies.
AB - Microcapsules, sized 1-1000 μm, offer a core-shell structure for encapsulating diverse substances, crucial in drug delivery and various applications. This work explores microcapsule deformation in microchannels with oscillating walls, utilizing a front-tracking-based 2D membrane model for Poiseuille flow. The microcapsules are created using a needle-based device, and the shell is made of a high-precision PLA bio-based resin, encapsulating the liquid core. The microcapsules are subjected to parallel plate compression experiments to assess their mechanical properties. Numerical simulations of the compression experiment are conducted, showing stress distribution within the capsule shell. A front-tracking-based 2D membrane model was applied to investigate the deformation of the microcapsule with a thin membrane shell and a liquid core in the Poiseuille flow. The microcapsules are further tested in an oscillating microchannel under different frequencies.
KW - Front Tracking Method
KW - Microcapsule
KW - Microchannel
KW - Oscillating Flow
KW - Parallel Plate Compression
UR - http://www.scopus.com/inward/record.url?scp=85205538785&partnerID=8YFLogxK
U2 - 10.1115/MNHMT2024-122522
DO - 10.1115/MNHMT2024-122522
M3 - Conference contribution
AN - SCOPUS:85205538785
T3 - Proceedings of ASME 2024 7th International Conference on Micro/Nanoscale Heat and Mass Transfer, MNHMT 2024
BT - Proceedings of ASME 2024 7th International Conference on Micro/Nanoscale Heat and Mass Transfer, MNHMT 2024
PB - American Society of Mechanical Engineers (ASME)
T2 - ASME 2024 7th International Conference on Micro/Nanoscale Heat and Mass Transfer, MNHMT 2024
Y2 - 5 August 2024 through 7 August 2024
ER -