Nickel-catalyzed regioselective hydrogen isotope exchange accelerated by 2-pyridones

Zhi Jiang Jiang, Si Han Xu, Yuhang Su, Erxun Hu, Jiawei Han, Jian Fei Bai, Bencan Tang, Jia Chen, Zhanghua Gao

Research output: Journal PublicationArticlepeer-review

1 Citation (Scopus)


A nickel-catalyzed hydrogen isotope exchange has been developed with acetone-d6 as the deuterium source. The reaction showed an improved kinetic feature of H/D exchange under the assistance of 2-pyridones, efficiently affording regioselective labeled aryl and alkyl carboxamides.

Original languageEnglish
Pages (from-to)384-387
Number of pages4
JournalChemical Communications
Issue number4
Publication statusPublished - 27 Nov 2023

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Catalysis
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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