Fluorescent DNA-Silver nanoclusters in food safety detection: From synthesis to application

Bingxuan Zhou, Imran Mahmood Khan, Xiaowei Ding, Sobia Niazi, Yin Zhang, Zhouping Wang

Research output: Journal PublicationReview articlepeer-review

3 Citations (Scopus)

Abstract

In recent years, the conventional preparation of silver nanoclusters (AgNCs) has attracted much attention due to their ultra-small size, tunable fluorescence, easy-to-engineer, as well as biocompatible material. Moreover, its great affinity towards cytosine bases on single-stranded DNA has led to the construction of biosensors, especially aptamers, for a broad variety of applications in food safety and environmental protection. In past years, numerous researchers paid attention to the construction of AgNCs aptasensor. Therefore, this review will be an effort to summarize the synthetic strategy along with the influences of factors on synthesis, categorize the sensing mechanism of aptamer-functionalized AgNCs biosensors, as well as their specific applications in food safety detection including heavy metal, toxin, and foodborne pathogenic bacteria. Furthermore, a brief conclusion and outlook regarding the prospects and challenges of their applications in food safety were drawn in line with the developments in DNA-AgNCs.

Original languageEnglish
Article number125834
JournalTalanta
Volume273
DOIs
Publication statusPublished - 1 Jun 2024

Keywords

  • Aptamer
  • Detection mechanism
  • Food safety
  • Silver nanoclusters
  • Synthesis

ASJC Scopus subject areas

  • Analytical Chemistry

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