Equilibrium Population

M. Haque, K. E. Holsinger

Research output: Chapter in Book/Conference proceedingBook Chapterpeer-review


When a population is in equilibrium, both genotype and allele frequencies remain constant from one generation to the next. If a population satisfies the conditions necessary to ensure that genotypes are in Hardy-Weinberg proportions, it follows that it is also in equilibrium. Even if a population does not satisfy the Hardy-Weinberg conditions, however, it may still be in equilibrium. The frequency of recessive alleles preventing individual monkey flower plants from producing pollen, for example, is likely to represent a balance between the tendency of natural selection to eliminate the recessive allele and recurrent mutation that tends to increase its frequency. A population in which such forces are balanced might be said to be in dynamic equilibrium. Two dynamic equilibrium points in a gene regulatory network correspond to biological switch to a gene circuit.

Original languageEnglish
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Number of pages3
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
Publication statusPublished - 27 Feb 2013
Externally publishedYes


  • Akt proteins
  • Biological switch
  • Bistability
  • Differential equations
  • Dynamic equilibrium
  • Gene regulatory circuits
  • Genotype and allele frequencies
  • Hardy-Weinberg proportions and conditions
  • Mathematical models
  • Monkey flower plants
  • P53 protein

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (all)
  • Biochemistry, Genetics and Molecular Biology (all)
  • Medicine (all)


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