Early age-related macular degeneration detection by focal biologically inspired feature

Jun Cheng, Damon Wing Kee Wong, Xiangang Cheng, Jiang Liu, Ngan Meng Tan, Mayuri Bhargava, Chui Ming Gemmy Cheung, Tien Yin Wong

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

25 Citations (Scopus)

Abstract

Age-related macular degeneration (AMD) is a leading cause of vision loss. The presence of drusen are often associated to AMD. Drusen are tiny yellowish-white extracellular buildup present around the macular region of the retina. Clinically, ophthalmologists examine the area around the macula to determine the presence and severity of drusen. However, manual identification and recognition of drusen is subjective, time consuming and expensive. To reduce manual workload and facilitate large-scale early AMD screening, it is essential to detect drusen automatically. In this paper, we propose to use biologically inspired features (BIF) for the purpose of AMD detection. The optic disc and macula are detected to determine a focal region around macula for feature extraction. The extracted features are then classified using support vector machines (SVM). Our experimental results, tested on 350 images, demonstrate that the biologically inspired features from the focal region is effective for drusen detection with a sensitivity of 86.3% and specificity of 91.9%. The results of our proposed approach can be used to reduce workload of ophthalmologists and diagnosis cost.

Original languageEnglish
Title of host publication2012 IEEE International Conference on Image Processing, ICIP 2012 - Proceedings
Pages2805-2808
Number of pages4
DOIs
Publication statusPublished - 2012
Externally publishedYes
Event2012 19th IEEE International Conference on Image Processing, ICIP 2012 - Lake Buena Vista, FL, United States
Duration: 30 Sep 20123 Oct 2012

Publication series

NameProceedings - International Conference on Image Processing, ICIP
ISSN (Print)1522-4880

Conference

Conference2012 19th IEEE International Conference on Image Processing, ICIP 2012
Country/TerritoryUnited States
CityLake Buena Vista, FL
Period30/09/123/10/12

Keywords

  • biologically inspired feature
  • drusen detection
  • retinal image

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Information Systems

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