Domain prior based superpixel propagation for optic cup localization

Ngan Meng Tan, Yanwu Xu, Jiang Liu, Wooi Boon Goh, Carol Cheung, Tin Aung, Tien Yin Wong

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

In this paper, we present an unsupervised framework using domain priors extracted from the primary structures of the optic nerve head for automated optic cup localization. Our approach provides 3 major contributions. First, we identify a new domain prior, optic cup origin. This prior is derived from the physiological understanding that the central retinal vessels traces its origin from the optic cup before extending to the rest of the retinal. Second, we propose extracting the features of the optic nerve head from superpixels, which are obtained from low-level grouping and have more natural and descriptive features than pixel based techniques. Third, the domain knowledge comprising of optic cup origin and cup pallor, and the extracted features from superpixels are then used to drive a similarity-based label propagation and refinement scheme for the optic cup localization. Our approach was validated on a clinical online dataset, ORIGA-light, of 650 population-based images. Overall, our approach is able to achieve a 32.2% non-overlap ratio (m1), a 33.8% relative absolute area difference (m2) and a 10.6% absolute CDR error (δ).

Original languageEnglish
Title of host publicationISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro
Pages880-883
Number of pages4
DOIs
Publication statusPublished - 2013
Externally publishedYes
Event2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 - San Francisco, CA, United States
Duration: 7 Apr 201311 Apr 2013

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013
Country/TerritoryUnited States
CitySan Francisco, CA
Period7/04/1311/04/13

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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