Disc-Aware Ensemble Network for Glaucoma Screening from Fundus Image

Huazhu Fu, Jun Cheng, Yanwu Xu, Changqing Zhang, Damon Wing Kee Wong, Jiang Liu, Xiaochun Cao

Research output: Journal PublicationArticlepeer-review

252 Citations (Scopus)


Glaucoma is a chronic eye disease that leads to irreversible vision loss. Most of the existing automatic screening methods first segment the main structure and subsequently calculate the clinical measurement for the detection and screening of glaucoma. However, these measurement-based methods rely heavily on the segmentation accuracy and ignore various visual features. In this paper, we introduce a deep learning technique to gain additional image-relevant information and screen glaucoma from the fundus image directly. Specifically, a novel disc-aware ensemble network for automatic glaucoma screening is proposed, which integrates the deep hierarchical context of the global fundus image and the local optic disc region. Four deep streams on different levels and modules are, respectively, considered as global image stream, segmentation-guided network, local disc region stream, and disc polar transformation stream. Finally, the output probabilities of different streams are fused as the final screening result. The experiments on two glaucoma data sets (SCES and new SINDI data sets) show that our method outperforms other state-of-the-art algorithms.

Original languageEnglish
Article number8359118
Pages (from-to)2493-2501
Number of pages9
JournalIEEE Transactions on Medical Imaging
Issue number11
Publication statusPublished - Nov 2018
Externally publishedYes


  • Deep learning
  • glaucoma screening
  • neural network
  • optic disc segmentation

ASJC Scopus subject areas

  • Software
  • Radiological and Ultrasound Technology
  • Computer Science Applications
  • Electrical and Electronic Engineering


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