Continuous protein recovery using a liquid - Solid circulating fluidized bed ion exchange system: Modelling and experimental studies

Q. Lan, J. X. Zhu, A. S. Bassi, A. Margaritis, Y. Zheng, G. E. Rowe

Research output: Journal PublicationArticlepeer-review

43 Citations (Scopus)

Abstract

In this study, a continuous protein recovery process using a Liquid-Solid Circulating Fluidized Bed (LSCFB) ion exchange system is described and a model with known kinetics has been developed. Experiments and computer simulations using Matlab are conducted at different operating conditions. The effects of hydrodynamic parameters and kinetic parameters on the performance of the LSCB ion exchange system are discussed. The model is shown to be applicable for the design of LSCFB ion exchange systems for protein recovery.

Original languageEnglish
Pages (from-to)858-866
Number of pages9
JournalCanadian Journal of Chemical Engineering
Volume78
Issue number5
DOIs
Publication statusPublished - 2000
Externally publishedYes

Keywords

  • Continuous ion exchange
  • Continuous protein recovery
  • Ion exchange chromatography
  • Liquid-solid circulating fluidized bed

ASJC Scopus subject areas

  • Chemical Engineering (all)

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