Abstract
A liquid-solid circulating fluidized bed (LSCFB) continuous ion-exchange extraction system has been investigated for total protein recovery from whey solutions under various operating conditions. The effectiveness of a dynamic seal was evaluated between the riser and the downcomer, and the best conditions for the establishment of this seal were established. Start-up studies indicated that the system is robust and stable. Under optimal conditions, a productivity of 8.2 g of total protein removed per hour per kilogram of resin was achieved with a protein removal efficiency of 78.4%. However, higher overall protein recovery of up to 90% was also achieved under other conditions, with lower protein concentration in the effluent and a lower overall productivity.
Original language | English |
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Pages (from-to) | 157-163 |
Number of pages | 7 |
Journal | Biotechnology and Bioengineering |
Volume | 78 |
Issue number | 2 |
DOIs | |
Publication status | Published - 20 Apr 2002 |
Externally published | Yes |
Keywords
- Continuous ion exchange
- Liquid-solid circulating fluidized bed
- Whey proteins
- Whole broth recovery
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Applied Microbiology and Biotechnology