TY - JOUR
T1 - Chemical composition and bioactivity of essential oils from Cistus ladanifer L., Pistacia lentiscus L., and Matricaria chamomilla L
AU - Benali, Taoufiq
AU - Laghmari, Mustapha
AU - Touhtouh, Jihane
AU - Aanniz, Tarik
AU - Lemhadri, Ahmed
AU - Daoudi, Mostapha Drissi
AU - Bouyahya, Abdelhakim
AU - Lee, Learn Han
AU - Ullah, Riaz
AU - Alotaibi, Amal
AU - Akhazzane, Mohamed
AU - Zengin, Gokhan
AU - Hammani, Khalil
N1 - Publisher Copyright:
© 2024
PY - 2024/10
Y1 - 2024/10
N2 - The objective of this study was to characterize the volatile compounds from the aerial part of Cistus ladanifer L., Pistacia lentiscus L., and Matricaria chamomilla L., members of Cistaceae, Anacardiaceae, and Asteraceae families, respectively; and assess their potential antioxidant, antimicrobial, and enzyme inhibitory properties. The essential oils were analyzed using gas chromatography-mass spectrometry (GC-MS-MS) analysis. The outcomes revealed distinct chemical profiles indicative of specific chemotypes within each species. Indeed, M. chamomilla essential oil (MCEO) contained sabinene (16.03 %), camphor (11.22 %), 3,6-dihydrochamazulene (14.22 %), and chamazulene (12.84 %) as its primary constituents. C. ladanifer essential oil (CLEO) prominently featured camphene (31.5 %), α-pinene (15.76%), and bornyl acetate (15.73 %), while P. lentiscus essential oil (PLEO) was rich in D-limonene (21 %), β-myrcene (14.89 %), α-pinene (13.93 %), and terpinen-4-ol (9.75 %). Remarkably, PLEO exhibited significant antioxidant activity across multiple assays, demonstrating inhibitory values of 72.07 ± 4.06 mg TE/g of extract (Cuprac), 45.74 ± 1.23 mg TE/g of extract (FRAP), 30.89 ± 1.69 mg EDTAE/g of extract (Chelating), 26.71 ± 1.84 mmol TE/g of extract (Phosphomolybdenum), 15.55 ± 0.84 mg TE/g of extract (ABTS), and 2.30 ± 0.22 mg TE/g of extract (DPPH). The results showed that the microorganisms under examination varied in their sensitivity to essential oils and the inhibitory zone ranged between 25 and 57 mm. The inhibitory effects of the essential oils were investigated against enzymes associated with human pathologies. As findings, CLEO demonstrated substantial inhibition of tyrosinase (10.22 ± 0.13 mg KAE/g of extract) and acetylcholinesterase (4.71 ± 0.97 mg GALAE/g of extract), outperforming other essential oils that displayed moderate activities. These important biological effects of the oils tested qualify these plants as an interesting source of phytochemicals with medicinal actions.
AB - The objective of this study was to characterize the volatile compounds from the aerial part of Cistus ladanifer L., Pistacia lentiscus L., and Matricaria chamomilla L., members of Cistaceae, Anacardiaceae, and Asteraceae families, respectively; and assess their potential antioxidant, antimicrobial, and enzyme inhibitory properties. The essential oils were analyzed using gas chromatography-mass spectrometry (GC-MS-MS) analysis. The outcomes revealed distinct chemical profiles indicative of specific chemotypes within each species. Indeed, M. chamomilla essential oil (MCEO) contained sabinene (16.03 %), camphor (11.22 %), 3,6-dihydrochamazulene (14.22 %), and chamazulene (12.84 %) as its primary constituents. C. ladanifer essential oil (CLEO) prominently featured camphene (31.5 %), α-pinene (15.76%), and bornyl acetate (15.73 %), while P. lentiscus essential oil (PLEO) was rich in D-limonene (21 %), β-myrcene (14.89 %), α-pinene (13.93 %), and terpinen-4-ol (9.75 %). Remarkably, PLEO exhibited significant antioxidant activity across multiple assays, demonstrating inhibitory values of 72.07 ± 4.06 mg TE/g of extract (Cuprac), 45.74 ± 1.23 mg TE/g of extract (FRAP), 30.89 ± 1.69 mg EDTAE/g of extract (Chelating), 26.71 ± 1.84 mmol TE/g of extract (Phosphomolybdenum), 15.55 ± 0.84 mg TE/g of extract (ABTS), and 2.30 ± 0.22 mg TE/g of extract (DPPH). The results showed that the microorganisms under examination varied in their sensitivity to essential oils and the inhibitory zone ranged between 25 and 57 mm. The inhibitory effects of the essential oils were investigated against enzymes associated with human pathologies. As findings, CLEO demonstrated substantial inhibition of tyrosinase (10.22 ± 0.13 mg KAE/g of extract) and acetylcholinesterase (4.71 ± 0.97 mg GALAE/g of extract), outperforming other essential oils that displayed moderate activities. These important biological effects of the oils tested qualify these plants as an interesting source of phytochemicals with medicinal actions.
KW - Acetylcholinesterase
KW - Diabetes
KW - Enzyme inhibition
KW - Essential oils
KW - Oxidative stress
KW - Tyrosinase
KW - α-amylase
KW - α-glucosidase
UR - http://www.scopus.com/inward/record.url?scp=85200492666&partnerID=8YFLogxK
U2 - 10.1016/j.bse.2024.104880
DO - 10.1016/j.bse.2024.104880
M3 - Article
AN - SCOPUS:85200492666
SN - 0305-1978
VL - 116
JO - Biochemical Systematics and Ecology
JF - Biochemical Systematics and Ecology
M1 - 104880
ER -
