Automatic Segmentation of Cortex and Nucleus in Anterior Segment OCT Images

Pengshuai Yin, Mingkui Tan, Huaqing Min, Yanwu Xu, Guanghui Xu, Qingyao Wu, Yunfei Tong, Higashita Risa, Jiang Liu

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

4 Citations (Scopus)

Abstract

We propose a pipeline for automatically segmenting cortex and nucleus in a 360-degree anterior segment optical coherence tomography (AS-OCT) image. The proposed pipeline consists of a U-shaped network followed by a shape template. The U-shaped network predicts a mask for cortex and nucleus. However, the boundary between cortex and nucleus is weak, so that the boundary of the prediction is an irregular shape and does not satisfy the physiological structure of nucleus. To address this problem, in the second step, we design a shape template according to the physiological structure of nucleus to refine the boundary. Our method integrates both appearance and structure information. The accuracy is measured by the normalized mean squared error (NMSE) between ground truth line and predicted line. We achieve NMSE 7.09/7.94 for nucleus top/bottom boundary and 2.49/2.43 for cortex top/bottom boundary.

Original languageEnglish
Title of host publicationComputational Pathology and Ophthalmic Medical Image Analysis - First International Workshop, COMPAY 2018, and 5th International Workshop, OMIA 2018, Held in Conjunction with MICCAI 2018, Proceedings
EditorsZeike Taylor, Hrvoje Bogunovic, David Snead, Mona K. Garvin, Xin Jan Chen, Francesco Ciompi, Yanwu Xu, Lena Maier-Hein, Mitko Veta, Emanuele Trucco, Danail Stoyanov, Nasir Rajpoot, Jeroen van der Laak, Anne Martel, Stephen McKenna
PublisherSpringer Verlag
Pages269-276
Number of pages8
ISBN (Print)9783030009489
DOIs
Publication statusPublished - 2018
Externally publishedYes
Event1st International Workshop on Computational Pathology, COMPAY 2018 and 5th International Workshop on Ophthalmic Medical Image Analysis, OMIA 2018 Held in Conjunction with MICCAI 2018 - Granada, Spain
Duration: 16 Sep 201820 Sep 2018

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11039 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference1st International Workshop on Computational Pathology, COMPAY 2018 and 5th International Workshop on Ophthalmic Medical Image Analysis, OMIA 2018 Held in Conjunction with MICCAI 2018
Country/TerritorySpain
CityGranada
Period16/09/1820/09/18

Keywords

  • AS-OCT
  • Image segmentation
  • SS-OCT

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science (all)

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