Automatic grading of nuclear cataracts from slit-lamp lens images using group sparsity regression

Yanwu Xu, Xinting Gao, Stephen Lin, Damon Wing Kee Wong, Jiang Liu, Dong Xu, Ching Yu Cheng, Carol Y. Cheung, Tien Yin Wong

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

44 Citations (Scopus)

Abstract

Cataracts, which result from lens opacification, are the leading cause of blindness worldwide. Current methods for determining the severity of cataracts are based on manual assessments that may be weakened by subjectivity. In this work, we propose a system to automatically grade the severity of nuclear cataracts from slit-lamp images. We introduce a new feature for cataract grading together with a group sparsity-based constraint for linear regression, which performs feature selection, parameter selection and regression model training simultaneously. In experiments on a large database of 5378 images, our system outperforms the state-of-the-art by yielding with respect to clinical grading a mean absolute error (ε) of 0.336, a 69.0% exact integral agreement ratio (R0), a 85.2% decimal grading error ≤ 0.5 (Re0.5), and a 98.9% decimal grading error ≤ 1.0 (Re1.0). Through a more objective grading of cataracts using our proposed system, there is potential for better clinical management of the disease.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI 2013 - 16th International Conference, Proceedings
Pages468-475
Number of pages8
EditionPART 2
DOIs
Publication statusPublished - 2013
Externally publishedYes
Event16th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2013 - Nagoya, Japan
Duration: 22 Sep 201326 Sep 2013

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume8150 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference16th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2013
Country/TerritoryJapan
CityNagoya
Period22/09/1326/09/13

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science (all)

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