Association of CCR5 Δ32 with reduced risk of asthma

Ian P. Hall, Amanda Wheatley, Gordon Christie, Catherine McDougall, Richard Hubbard, Peter J. Helms

Research output: Journal PublicationArticlepeer-review

102 Citations (Scopus)

Abstract

We report that individuals carrying the CCR5Δ32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma. These data suggest a possible explanation for the high prevalence of this mutation in the general population.

Original languageEnglish
Pages (from-to)1264-1265
Number of pages2
JournalThe Lancet
Volume354
Issue number9186
DOIs
Publication statusPublished - 9 Oct 1999
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (all)

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