An update on electrostatic powder coating for pharmaceuticals

Qingliang Yang, Yingliang Ma, Jesse Zhu, Kwok Chow, Kaiqi Shi

Research output: Journal PublicationReview articlepeer-review

29 Citations (Scopus)

Abstract

Derived from dry powder coating of metals, electrostatic powder coating for pharmaceuticals is a technology for coating drug solid dosage forms. In this technology, coating powders, containing coating polymers, pigments, and other excipients, are directly sprayed onto the surface of the solid dosage forms through an electrostatic gun without using any organic solvent or water. The deposited coating powders are further cured to form a coating film. Electrostatic powder coating technology has many advantages compared to other pharmaceutical coating methods. It can eliminate the limitations caused by the organic solvent in solvent coating such as environmental issues and health problems. And electrostatic powder coating technology also surpasses aqueous coating due to its shorter processing time and less energy consumption, leading to a lower overall cost. Furthermore, the utilization of electrical attraction can promote the movement of coating powders towards the substrate, leading to an enhanced coating powder adhesion and coating efficiency, which make it more promising compared to other dry coating technologies. The objective of this review is to summarize the coating principles, apparatus, and formulations of different electrostatic powder coating technologies, giving their advantages and limitations and also analyzing the future application in the industry for each technology.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalParticuology
Volume31
DOIs
Publication statusPublished - 1 Apr 2017
Externally publishedYes

Keywords

  • Curing
  • Electrostatic powder coating
  • Film formation
  • Plasticizers
  • Powder adhesion
  • Solid dosage forms

ASJC Scopus subject areas

  • Chemical Engineering (all)
  • Materials Science (all)

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