A-fibres sprouting from lamina I into lamina II of spinal dorsal horn after peripheral nerve injury in rats

Qing Ping Ma, Li Tian

Research output: Journal PublicationArticlepeer-review

11 Citations (Scopus)

Abstract

We have examined the labeling pattern in the spinal dorsal horn by an intra-sciatic nerve injection of cholera toxin B subunit conjugated horseradish peroxidase (HRP) after transection of the posterior cutaneous nerve and inferior gluteal nerve, and found that the cholera toxin B subunit conjugated HRP labeling in lamina I was expanding into lamina II and there was a shrinking gap between lamina I and lamina III. This result suggests that A-fibre sprouting arise after peripheral nerve injury, but mainly from small calibre Aδ-fibres which terminate in lamina I.

Original languageEnglish
Pages (from-to)137-140
Number of pages4
JournalBrain Research
Volume904
Issue number1
DOIs
Publication statusPublished - 15 Jun 2001
Externally publishedYes

Keywords

  • Bandeiraea simplicifolia isolectin B4 (IB4)
  • Cholera toxin B subunit (CTB)
  • Dorsal root ganglia (DRG)
  • Primary afferent

ASJC Scopus subject areas

  • Neuroscience (all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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