Enzyme-MXene Nanosheets: Fabrication and Application in Electrochemical Detection of H2O2

Bao Kai Ma, Mian Li, Ling Zhi Cheong, Xin Chu Weng, Cai Shen, Qing Huang

Research output: Journal PublicationArticlepeer-review

20 Citations (Scopus)


Two-dimensional MXene nanosheets with vertical junction structure was employed for easy immobilization of horse radish peroxidase enzymes to fabricate the electrochemical hydrogen peroxide (H2O2) biosensor. The synthesized MXene nanosheets exhibited large specific area, excellent electronic conductivity and good dispersion in aqueous phase. Horse Radish Peroxidase (HRP) enzymes molecules immobilized on MXene/chitosan/GCE electrode demonstrated good electrocatalytic activity toward reduction of H2O2. The fabricated HRP@MXene/chitosan/GCE biosensor exhibited a wide linear range from 5 to 1650 μmol∙L-1, a limit of detection of 0.74 μmol∙L-1 and good operation stability. The fabricated biosensor was successfully employed for detection of trace level of H2O2 in both solid and liquid food.

Translated title of the contribution酶-二维MXene复合材料的制备及其电化学检测H2O2的应用
Original languageEnglish
Pages (from-to)131-138
Number of pages8
JournalWuji Cailiao Xuebao/Journal of Inorganic Materials
Issue number1
Publication statusPublished - 1 Jan 2020
Externally publishedYes


  • Biosensor
  • Horse radish peroxidase
  • Hydrogen peroxide
  • MXene nanosheets

ASJC Scopus subject areas

  • Materials Science (all)
  • Inorganic Chemistry


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