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TM-UNet: Token-Memory Enhanced Sequential Modeling for Efficient Medical Image Segmentation

  • Yaxuan Jiao
  • , Qing XU
  • , Yuxiang Luo
  • , Xiangjian He
  • , Zhen Chen*
  • , Wenting Duan
  • *Corresponding author for this work

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

Medical image segmentation is essential for clinical diagnosis and treatment planning. Although transformer-based methods have achieved remarkable results, their high computational cost hinders clinical deployment. To address this issue, we propose TM-UNet, a novel lightweight framework that integrates token sequence modeling with an efficient memory mechanism for efficient medical segmentation. Specifically, we introduce a multi-scale token-memory (MSTM) block that transforms 2D spatial features into token sequences through strategic spatial scanning, leveraging matrix memory cells to selectively retain and propagate discriminative contextual information across tokens. This novel token-memory mechanism acts as a dynamic knowledge store that captures longrange dependencies with linear complexity, enabling efficient global reasoning without redundant computation. Our MSTM block further incorporates exponential gating to identify token effectiveness and multi-scale contextual extraction via parallel pooling operations, enabling hierarchical representation learning without computational overhead. Extensive experiments demonstrate that TM-UNet outperforms state-of-theart methods across diverse medical segmentation tasks with substantially reduced computation cost. The code is available at https://github.com/xq141839/TM-UNet.

Original languageEnglish
Title of host publicationISBI 2026 - 23rd IEEE International Symposium on Biomedical Imaging
PublisherIEEE Computer Society
ISBN (Electronic)9798331577636
DOIs
Publication statusPublished - 2026
Event23rd IEEE International Symposium on Biomedical Imaging, ISBI 2026 - London, United Kingdom
Duration: 8 Apr 202611 Apr 2026

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2026-April
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference23rd IEEE International Symposium on Biomedical Imaging, ISBI 2026
Country/TerritoryUnited Kingdom
CityLondon
Period8/04/2611/04/26

Free Keywords

  • lightweight architecture
  • Medical image segmentation
  • sequence modeling

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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