TY - GEN
T1 - TM-UNet
T2 - 23rd IEEE International Symposium on Biomedical Imaging, ISBI 2026
AU - Jiao, Yaxuan
AU - XU, Qing
AU - Luo, Yuxiang
AU - He, Xiangjian
AU - Chen, Zhen
AU - Duan, Wenting
N1 - Publisher Copyright:
© 2026 IEEE.
PY - 2026
Y1 - 2026
N2 - Medical image segmentation is essential for clinical diagnosis and treatment planning. Although transformer-based methods have achieved remarkable results, their high computational cost hinders clinical deployment. To address this issue, we propose TM-UNet, a novel lightweight framework that integrates token sequence modeling with an efficient memory mechanism for efficient medical segmentation. Specifically, we introduce a multi-scale token-memory (MSTM) block that transforms 2D spatial features into token sequences through strategic spatial scanning, leveraging matrix memory cells to selectively retain and propagate discriminative contextual information across tokens. This novel token-memory mechanism acts as a dynamic knowledge store that captures longrange dependencies with linear complexity, enabling efficient global reasoning without redundant computation. Our MSTM block further incorporates exponential gating to identify token effectiveness and multi-scale contextual extraction via parallel pooling operations, enabling hierarchical representation learning without computational overhead. Extensive experiments demonstrate that TM-UNet outperforms state-of-theart methods across diverse medical segmentation tasks with substantially reduced computation cost. The code is available at https://github.com/xq141839/TM-UNet.
AB - Medical image segmentation is essential for clinical diagnosis and treatment planning. Although transformer-based methods have achieved remarkable results, their high computational cost hinders clinical deployment. To address this issue, we propose TM-UNet, a novel lightweight framework that integrates token sequence modeling with an efficient memory mechanism for efficient medical segmentation. Specifically, we introduce a multi-scale token-memory (MSTM) block that transforms 2D spatial features into token sequences through strategic spatial scanning, leveraging matrix memory cells to selectively retain and propagate discriminative contextual information across tokens. This novel token-memory mechanism acts as a dynamic knowledge store that captures longrange dependencies with linear complexity, enabling efficient global reasoning without redundant computation. Our MSTM block further incorporates exponential gating to identify token effectiveness and multi-scale contextual extraction via parallel pooling operations, enabling hierarchical representation learning without computational overhead. Extensive experiments demonstrate that TM-UNet outperforms state-of-theart methods across diverse medical segmentation tasks with substantially reduced computation cost. The code is available at https://github.com/xq141839/TM-UNet.
KW - lightweight architecture
KW - Medical image segmentation
KW - sequence modeling
UR - https://www.scopus.com/pages/publications/105041676944
U2 - 10.1109/ISBI61048.2026.11515341
DO - 10.1109/ISBI61048.2026.11515341
M3 - Conference contribution
AN - SCOPUS:105041676944
T3 - Proceedings - International Symposium on Biomedical Imaging
BT - ISBI 2026 - 23rd IEEE International Symposium on Biomedical Imaging
PB - IEEE Computer Society
Y2 - 8 April 2026 through 11 April 2026
ER -