Abstract
In this paper a pulse vaccination SIR model with periodic infection rate β(t) is studied. The basic reproductive number R 0 is defined. The dynamical behavior of the model is analyzed. It is proved that the infection-free periodic solution is globally stable if R 0 < 1. The infection-free periodic solution is unstable and the disease will uniform persistence when R 0 > 1. We use standard bifurcation theory to show the existence of the positive periodic solution when R 0 → 1 +. Numerical simulation can give suggestion, the system has a unique positive periodic, and it is globally stable when R 0 > 1.
| Original language | English |
|---|---|
| Pages (from-to) | 409-432 |
| Number of pages | 24 |
| Journal | International Journal of Biomathematics |
| Volume | 1 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Dec 2008 |
Keywords
- Epidemic model
- globally stable
- pulse vaccination
- the basic reproductive number
- the infection-free periodic solution
- the positive periodic solution
- uniform persistence
ASJC Scopus subject areas
- Modelling and Simulation
- Applied Mathematics