In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation

Jonathan C. Moore; Rowena A. Howie; Samuel L. Bourne; Gareth N. Jenkins; Peter Licence; Martyn Poliakoff; Michael W. George

doi:10.1021/acssuschemeng.9b04347

In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation

Jonathan C. Moore
, Rowena A. Howie
, Samuel L. Bourne
, Gareth N. Jenkins
, Peter Licence
, Martyn Poliakoff
, Michael W. George

Department of Chemical and Environmental Engineering

Research output: Journal Publication › Article › peer-review

7 Citations (Scopus)

Abstract

A method has been developed for the in situ sulfidation of Pd/C under continuous flow. The approach provides a cheap, sustainable, and operationally convenient method for chemoselective conjugate reduction by continuous hydrogenation. High conversions and excellent selectivities were obtained for olefin reduction in α/β-unsaturated carbonyl compounds in the presence of hydrogenatively sensitive functionalities. The methodology was analyzed with a green metric system to highlight the sustainability features of the process.

Original language	English
Pages (from-to)	16814-16819
Number of pages	6
Journal	ACS Sustainable Chemistry and Engineering
Volume	7
Issue number	19
DOIs	https://doi.org/10.1021/acssuschemeng.9b04347
Publication status	Published - 7 Oct 2019

ASJC Scopus subject areas

General Chemistry
Environmental Chemistry
General Chemical Engineering
Renewable Energy, Sustainability and the Environment

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10.1021/acssuschemeng.9b04347

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title = "In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation",

abstract = "A method has been developed for the in situ sulfidation of Pd/C under continuous flow. The approach provides a cheap, sustainable, and operationally convenient method for chemoselective conjugate reduction by continuous hydrogenation. High conversions and excellent selectivities were obtained for olefin reduction in α/β-unsaturated carbonyl compounds in the presence of hydrogenatively sensitive functionalities. The methodology was analyzed with a green metric system to highlight the sustainability features of the process.",

author = "Moore, \{Jonathan C.\} and Howie, \{Rowena A.\} and Bourne, \{Samuel L.\} and Jenkins, \{Gareth N.\} and Peter Licence and Martyn Poliakoff and George, \{Michael W.\}",

note = "Publisher Copyright: Copyright {\textcopyright} 2019 American Chemical Society.",

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T2 - A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation

AU - Moore, Jonathan C.

AU - Howie, Rowena A.

AU - Bourne, Samuel L.

AU - Jenkins, Gareth N.

AU - Licence, Peter

AU - Poliakoff, Martyn

AU - George, Michael W.

PY - 2019/10/7

Y1 - 2019/10/7

N2 - A method has been developed for the in situ sulfidation of Pd/C under continuous flow. The approach provides a cheap, sustainable, and operationally convenient method for chemoselective conjugate reduction by continuous hydrogenation. High conversions and excellent selectivities were obtained for olefin reduction in α/β-unsaturated carbonyl compounds in the presence of hydrogenatively sensitive functionalities. The methodology was analyzed with a green metric system to highlight the sustainability features of the process.

AB - A method has been developed for the in situ sulfidation of Pd/C under continuous flow. The approach provides a cheap, sustainable, and operationally convenient method for chemoselective conjugate reduction by continuous hydrogenation. High conversions and excellent selectivities were obtained for olefin reduction in α/β-unsaturated carbonyl compounds in the presence of hydrogenatively sensitive functionalities. The methodology was analyzed with a green metric system to highlight the sustainability features of the process.

UR - https://www.scopus.com/pages/publications/85072939387

U2 - 10.1021/acssuschemeng.9b04347

DO - 10.1021/acssuschemeng.9b04347

M3 - Article

AN - SCOPUS:85072939387

SN - 2168-0485

VL - 7

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JO - ACS Sustainable Chemistry and Engineering

JF - ACS Sustainable Chemistry and Engineering

IS - 19

ER -

In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation

Abstract

ASJC Scopus subject areas

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