Hotspot Hunter: A computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes

Keyphrases

• Hunters 100%
• Proteome 100%
• Large-scale Screening 100%
• Computational System 100%
• Supertype 80%
• T Cell Epitope 40%
• Computational Tools 40%
• Protein Sequence 40%
• Human Leukocyte Antigen 40%
• Human Population 40%
• Peptide Vaccine 40%
• Result Prediction 40%
• Antigenic Diversity 40%
• Artificial Neural Network 20%
• Experimental Validation 20%
• Performance Prediction 20%
• Vaccine Development 20%
• T Cell Activation 20%
• Support Vector Machine Model 20%
• System Use 20%
• Web-based 20%
• Complex Allele 20%
• Target Selection 20%
• Human Leukocyte Antigen Class I 20%
• Automated Screening 20%
• Variant Strain 20%
• Computing Principles 20%
• Multiple Variants 20%
• Peptide Vaccine Design 20%
• Global View 20%
• Activation Function 20%
• Attribute Selection 20%
• Single Cell Protein 20%
• Antigenic Shift 20%
• Soft Computing 20%
• Protein Variants 20%
• Automated Selection 20%
• Robust Prediction 20%

Immunology and Microbiology

• Infectious Agent 100%
• Epitope 100%
• Vaccine Efficacy 80%
• T Cell 40%
• Amino Acid Sequence 40%
• Human Leukocyte Antigen 40%
• Allele 20%
• Immunotherapy 20%
• Receptor Type Tyrosine Protein Phosphatase C 20%
• Artificial Neural Network 20%
• T Cell Activation 20%
• Support Vector Machine 20%

Biochemistry, Genetics and Molecular Biology

• Infectious Agent 100%
• Proteome 100%
• T Cell 60%
• Human Leukocyte Antigen 60%
• Peptide Sequence 40%
• Allele 20%
• Artificial Neural Network 20%
• Support Vector Machine 20%
• Cell Activation 20%