Abstract
A novel method is proposed for quantifying the Raman intensity as a function of gold mass in a single cell based on the Raman mapping and inductively coupled plasma-mass spectrometry techniques. A high-efficiency plasmonic photothermal therapy has also been achieved by adjusting the laser wavelength, laser power and exposure time, resulting in most of the HL-7702 cells surviving, whereas most of the HepG2 cells get damaged.
| Original language | English |
|---|---|
| Pages (from-to) | 2245-2259 |
| Number of pages | 15 |
| Journal | Nanomedicine |
| Volume | 13 |
| Issue number | 18 |
| DOIs | |
| Publication status | Published - 1 Sept 2018 |
Free Keywords
- ICP-MS
- Raman mapping
- cellular uptake
- cytotoxicity
- gold nanoparticles
- human hepatic immortalized cell lines (HL-7702)
- human hepatocellular carcinoma cell lines (HepG2)
- plasmonic photothermal therapy
- surface enhanced Raman scattering (SERS)
ASJC Scopus subject areas
- Bioengineering
- Medicine (miscellaneous)
- Biomedical Engineering
- General Materials Science
