TY - JOUR
T1 - Edible domestic animal blood products for biomedical and disease treatment applications
AU - Cao, Zhi
AU - Khan, Imran Mahmood
AU - Niu, Xiangrui
AU - Hu, Yang
AU - Duan, Zhuang
AU - Fang, Qiang
AU - Wang, Zhouping
AU - Yang, Junsong
N1 - Publisher Copyright:
© 2025 The Author(s)
PY - 2025/1
Y1 - 2025/1
N2 - Edible blood products from domestic livestock are high-value derivatives produced during slaughter, with significant potential in biomedicine and disease treatment. Livestock blood is rich in proteins, peptides, iron, vitamins and other bioactive substances. Among them, functional proteins and peptides have been widely studied for their prominent roles in drug delivery, immune regulation, anti-infection and antioxidation. They significantly impact cancer treatment and immune regulation, providing valuable resources for innovation in the food and pharmaceutical industries. The development and utilization of livestock blood products offer innovative solutions for disease treatment and promote the sustainable development of the food and pharmaceutical industries by reducing the environmental burden of blood waste. However, challenges such as the complexity of blood composition, the variability of bioactive compound effectiveness, and the need for advanced purification techniques limit their broader applications. Additionally, regulatory and safety concerns must be addressed for therapeutic suitability. This review highlights the recent advancements in the biomedical applications of livestock blood products in biomedicine, addressing these challenges and emphasizing their potential to reduce environmental waste and promote sustainable development. This review consolidates current knowledge to provide a foundation for future research, fostering innovation in disease intervention and therapy while addressing utilization barriers.
AB - Edible blood products from domestic livestock are high-value derivatives produced during slaughter, with significant potential in biomedicine and disease treatment. Livestock blood is rich in proteins, peptides, iron, vitamins and other bioactive substances. Among them, functional proteins and peptides have been widely studied for their prominent roles in drug delivery, immune regulation, anti-infection and antioxidation. They significantly impact cancer treatment and immune regulation, providing valuable resources for innovation in the food and pharmaceutical industries. The development and utilization of livestock blood products offer innovative solutions for disease treatment and promote the sustainable development of the food and pharmaceutical industries by reducing the environmental burden of blood waste. However, challenges such as the complexity of blood composition, the variability of bioactive compound effectiveness, and the need for advanced purification techniques limit their broader applications. Additionally, regulatory and safety concerns must be addressed for therapeutic suitability. This review highlights the recent advancements in the biomedical applications of livestock blood products in biomedicine, addressing these challenges and emphasizing their potential to reduce environmental waste and promote sustainable development. This review consolidates current knowledge to provide a foundation for future research, fostering innovation in disease intervention and therapy while addressing utilization barriers.
KW - Animal blood products
KW - Bioactive peptide
KW - Disease treatment
KW - Functional protein
UR - https://www.scopus.com/pages/publications/105009126223
U2 - 10.1016/j.crbiot.2025.100308
DO - 10.1016/j.crbiot.2025.100308
M3 - Review article
AN - SCOPUS:105009126223
SN - 2590-2628
VL - 10
JO - Current Research in Biotechnology
JF - Current Research in Biotechnology
M1 - 100308
ER -