Data cleansing for computer models: A case study from immunology

Vladirnir Brusic; John Zeleznikow; Tiziana Sturniolo; Elisa Bono; Jürgen Hammer

doi:10.1109/ICONIP.1999.845663

Data cleansing for computer models: A case study from immunology

Vladirnir Brusic^*
, John Zeleznikow
, Tiziana Sturniolo
, Elisa Bono
, Jürgen Hammer

^*Corresponding author for this work

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

10 Citations (Scopus)

Abstract

Knowledge discovery from databases (KDD) in biology largely depends on the use of accurate computer models of biological processes. KDD applications in immunology include the discovery of vaccine targets and new functional relations within the immune system. We describe a process of development and refinement of artificial neural network models of the human HLA-DR1 molecule, useful for the discovery of peptide vaccines. High accuracy of these models was achieved by data cleansing techniques and by cyclical retraining using new data.

Original language	English
Title of host publication	ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	603-609
Number of pages	7
ISBN (Electronic)	0780358716, 9780780358713
DOIs	https://doi.org/10.1109/ICONIP.1999.845663
Publication status	Published - 1999
Externally published	Yes
Event	6th International Conference on Neural Information Processing, ICONIP 1999 - Perth, Australia Duration: 16 Nov 1999 → 20 Nov 1999

Publication series

Name	ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings
Volume	2

Conference

Conference	6th International Conference on Neural Information Processing, ICONIP 1999
Country/Territory	Australia
City	Perth
Period	16/11/99 → 20/11/99

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Artificial Intelligence
Computational Theory and Mathematics
Computer Networks and Communications
Statistics, Probability and Uncertainty

Access to Document

10.1109/ICONIP.1999.845663

Cite this

Brusic, V., Zeleznikow, J., Sturniolo, T., Bono, E., & Hammer, J. (1999). Data cleansing for computer models: A case study from immunology. In ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings (pp. 603-609). Article 845663 (ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings; Vol. 2). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICONIP.1999.845663

Brusic, Vladirnir ; Zeleznikow, John ; Sturniolo, Tiziana et al. / Data cleansing for computer models : A case study from immunology. ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings. Institute of Electrical and Electronics Engineers Inc., 1999. pp. 603-609 (ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings).

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title = "Data cleansing for computer models: A case study from immunology",

abstract = "Knowledge discovery from databases (KDD) in biology largely depends on the use of accurate computer models of biological processes. KDD applications in immunology include the discovery of vaccine targets and new functional relations within the immune system. We describe a process of development and refinement of artificial neural network models of the human HLA-DR1 molecule, useful for the discovery of peptide vaccines. High accuracy of these models was achieved by data cleansing techniques and by cyclical retraining using new data.",

author = "Vladirnir Brusic and John Zeleznikow and Tiziana Sturniolo and Elisa Bono and J{\"u}rgen Hammer",

note = "Publisher Copyright: {\textcopyright} 1999 IEEE.; 6th International Conference on Neural Information Processing, ICONIP 1999 ; Conference date: 16-11-1999 Through 20-11-1999",

year = "1999",

doi = "10.1109/ICONIP.1999.845663",

language = "English",

series = "ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings",

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Brusic, V, Zeleznikow, J, Sturniolo, T, Bono, E & Hammer, J 1999, Data cleansing for computer models: A case study from immunology. in ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings., 845663, ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings, vol. 2, Institute of Electrical and Electronics Engineers Inc., pp. 603-609, 6th International Conference on Neural Information Processing, ICONIP 1999, Perth, Australia, 16/11/99. https://doi.org/10.1109/ICONIP.1999.845663

Data cleansing for computer models: A case study from immunology. / Brusic, Vladirnir; Zeleznikow, John; Sturniolo, Tiziana et al.
ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings. Institute of Electrical and Electronics Engineers Inc., 1999. p. 603-609 845663 (ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings; Vol. 2).

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

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T1 - Data cleansing for computer models

T2 - 6th International Conference on Neural Information Processing, ICONIP 1999

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AU - Zeleznikow, John

AU - Sturniolo, Tiziana

AU - Bono, Elisa

AU - Hammer, Jürgen

PY - 1999

Y1 - 1999

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AB - Knowledge discovery from databases (KDD) in biology largely depends on the use of accurate computer models of biological processes. KDD applications in immunology include the discovery of vaccine targets and new functional relations within the immune system. We describe a process of development and refinement of artificial neural network models of the human HLA-DR1 molecule, useful for the discovery of peptide vaccines. High accuracy of these models was achieved by data cleansing techniques and by cyclical retraining using new data.

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U2 - 10.1109/ICONIP.1999.845663

DO - 10.1109/ICONIP.1999.845663

M3 - Conference contribution

AN - SCOPUS:84855879741

T3 - ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings

SP - 603

EP - 609

BT - ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

Y2 - 16 November 1999 through 20 November 1999

ER -

Brusic V, Zeleznikow J, Sturniolo T, Bono E, Hammer J. Data cleansing for computer models: A case study from immunology. In ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings. Institute of Electrical and Electronics Engineers Inc. 1999. p. 603-609. 845663. (ICONIP 1999, 6th International Conference on Neural Information Processing - Proceedings). doi: 10.1109/ICONIP.1999.845663

Data cleansing for computer models: A case study from immunology

Abstract

Publication series

Conference

UN SDGs

ASJC Scopus subject areas

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