Asclepius: A Spectrum Evaluation Benchmark for Medical Multi-Modal Large Language Models

Jie Liu, Wenxuan Wang, Yihang Su, Jingyuan Huan, Yudi Zhang, Cheng Yi Li, Wenting Chen, Xiaohan Xing, Kao Jung Chang, Linlin Shen, Michael R. Lyu

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

The significant breakthroughs of Medical Multi-Modal Large Language Models (Med-MLLMs) renovate modern healthcare with robust information synthesis and medical decision support. However, these models are often evaluated on benchmarks that are unsuitable for the Med-MLLMs due to the complexity of real-world diagnostics across diverse specialties. To address this gap, we introduce Asclepius, a novel Med-MLLM benchmark that comprehensively assesses Med-MLLMs in terms of: distinct medical specialties (cardiovascular, gas-troenterology, etc.) and different diagnostic capacities (perception, disease analysis, etc.). Grounded in 3 proposed core principles, Asclepius ensures a comprehensive evaluation by encompassing 15 medical specialties, stratifying into 3 main categories and 8 sub-categories of clinical tasks, and exempting overlap with existing VQA dataset. We further provide an in-depth analysis of 6 Med-MLLMs and compare them with 3 human specialists, providing insights into their competencies and limitations in various medical contexts. Our work not only advances the understanding of Med-MLLMs' capabilities but also sets a precedent for future evaluations and the safe deployment of these models in clinical environments.

Original languageEnglish
Title of host publicationLong Papers
EditorsWanxiang Che, Joyce Nabende, Ekaterina Shutova, Mohammad Taher Pilehvar
PublisherAssociation for Computational Linguistics (ACL)
Pages24181-24201
Number of pages21
ISBN (Electronic)9798891762510
Publication statusPublished - 2025
Externally publishedYes
Event63rd Annual Meeting of the Association for Computational Linguistics, ACL 2025 - Vienna, Austria
Duration: 27 Jul 20251 Aug 2025

Publication series

NameProceedings of the Annual Meeting of the Association for Computational Linguistics
Volume1
ISSN (Print)0736-587X

Conference

Conference63rd Annual Meeting of the Association for Computational Linguistics, ACL 2025
Country/TerritoryAustria
CityVienna
Period27/07/251/08/25

ASJC Scopus subject areas

  • Language and Linguistics
  • Linguistics and Language
  • Computer Science Applications

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