TY - GEN
T1 - Any-to-Any Vision-Language Model for Multimodal X-ray Imaging and Radiological Report Generation
AU - Molino, Daniele
AU - di Feola, Francesco
AU - Shen, Linlin
AU - Soda, Paolo
AU - Guarrasi, Valerio
N1 - Publisher Copyright:
© 2025 IEEE.
PY - 2025
Y1 - 2025
N2 - Generative models have revolutionized Artificial Intelligence (AI), particularly in multimodal applications. However, adapting these models to the medical domain poses unique challenges due to the complexity of medical data and the stringent need for clinical accuracy. In this work, we introduce a framework specifically designed for multimodal medical data generation. By enabling the generation of multi-view chest X-rays and their associated clinical report, it bridges the gap between general-purpose vision-language models and the specialized requirements of healthcare. Leveraging the MIMIC-CXR dataset, the proposed framework shows superior performance in generating high-fidelity images and semantically coherent reports. Our quantitative evaluation reveals significant results in terms of FID and BLEU scores, showcasing the quality of the generated data. Notably, our framework achieves comparable or even superior performance compared to real data on downstream disease classification tasks, underlining its potential as a tool for medical research and diagnostics. This study highlights the importance of domain-specific adaptations in enhancing the relevance and utility of generative models for clinical applications, paving the way for future advancements in synthetic multimodal medical data generation.
AB - Generative models have revolutionized Artificial Intelligence (AI), particularly in multimodal applications. However, adapting these models to the medical domain poses unique challenges due to the complexity of medical data and the stringent need for clinical accuracy. In this work, we introduce a framework specifically designed for multimodal medical data generation. By enabling the generation of multi-view chest X-rays and their associated clinical report, it bridges the gap between general-purpose vision-language models and the specialized requirements of healthcare. Leveraging the MIMIC-CXR dataset, the proposed framework shows superior performance in generating high-fidelity images and semantically coherent reports. Our quantitative evaluation reveals significant results in terms of FID and BLEU scores, showcasing the quality of the generated data. Notably, our framework achieves comparable or even superior performance compared to real data on downstream disease classification tasks, underlining its potential as a tool for medical research and diagnostics. This study highlights the importance of domain-specific adaptations in enhancing the relevance and utility of generative models for clinical applications, paving the way for future advancements in synthetic multimodal medical data generation.
KW - Chest X-rays
KW - Contrastive Learning
KW - Diffusion Models
KW - Generative AI
KW - Radiological Report
KW - Self-Supervised Learning
UR - https://www.scopus.com/pages/publications/105023982065
U2 - 10.1109/IJCNN64981.2025.11227399
DO - 10.1109/IJCNN64981.2025.11227399
M3 - Conference contribution
AN - SCOPUS:105023982065
T3 - Proceedings of the International Joint Conference on Neural Networks
BT - International Joint Conference on Neural Networks, IJCNN 2025 - Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2025 International Joint Conference on Neural Networks, IJCNN 2025
Y2 - 30 June 2025 through 5 July 2025
ER -