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渗透泵药物控释制剂包衣工艺研究进展

Translated title of the contribution: Recent Advances of Film Coating for Osmotic Drug Delivery Systems
  • Xin Yi Chen
  • , Feng Yuan
  • , Kai Qi Shi
  • , Gen Sheng Yang
  • , Qing Liang Yang*
  • *Corresponding author for this work

Research output: Journal PublicationReview articlepeer-review

Abstract

As one of the oral drug delivery system capable achieving constant drug release rate, osmotic pump is considered as the ultimate ideal drug delivery system. Compared with traditional oral preparation, osmotic pump could precisely control the drug release rate over a prolonged time period, significantly reducing the frequency of drug administrations and eliminating side effects caused by the fluctuation of drug plasma concentration. This review aims to summarize and discuss the newly developed manufacturing methods of the crucial coating film (semipermeable membrane) of the osmotic pump, focusing on the advantages and limitations of each fabricating method. The review also provides future perspectives of the promising applications of each manufacturing procedure for the osmotic pump.

Translated title of the contributionRecent Advances of Film Coating for Osmotic Drug Delivery Systems
Original languageChinese (Traditional)
Pages (from-to)1874-1879
Number of pages6
JournalChinese Pharmaceutical Journal
Volume56
Issue number23
DOIs
Publication statusPublished - 8 Dec 2021
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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